Literature DB >> 18574217

Cancer treatment and the ovary: the effects of chemotherapy and radiation.

Laurie E Cohen1.   

Abstract

Certain chemotherapeutic drugs ("alkylators") and radiation therapy are toxic to the ovaries, leading to both loss of sex steroid hormone production and infertility. Higher doses and older age at treatment are both associated with greater damage. Even patients with spontaneous menstrual cycles have evidence of decreased ovarian potential. Adolescents who are treated for cancer with these agents should be counseled about future fertility risks.

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Year:  2008        PMID： 18574217     DOI： 10.1196/annals.1429.023

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  7 in total

1.  Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: final results from CALGB trial 79809.

Authors:  C L Shapiro; S Halabi; V Hars; L Archer; D Weckstein; J Kirshner; W Sikov; E Winer; H J Burstein; C Hudis; C Isaacs; R Schilsky; E Paskett
Journal:  Eur J Cancer       Date:  2011-02-14       Impact factor: 9.162

Review 2.  Female reproductive health after childhood, adolescent, and young adult cancers: guidelines for the assessment and management of female reproductive complications.

Authors:  Monika L Metzger; Lillian R Meacham; Briana Patterson; Jacqueline S Casillas; Louis S Constine; Nobuko Hijiya; Lisa B Kenney; Marcia Leonard; Barbara A Lockart; Wendy Likes; Daniel M Green
Journal:  J Clin Oncol       Date:  2013-02-04       Impact factor: 44.544

3.  Unusual ovarian stromal tumor with radiation changes mimicking carcinoma.

Authors:  Olga L Bohn; Chengquan Zhao; Mirka W Jones
Journal:  J Cancer       Date:  2011-04-27       Impact factor: 4.207

4.  Successful Laparoscopic Resection of 7 mm Ovarian Mature Cystic Teratoma Associated with Anti-NMDAR Encephalitis.

Authors:  Masaru Hayashi; Emi Motegi; Koichi Honma; Nobuhide Masawa; Hideki Sakuta; Koichi Hirata; Yasushi Kaji; Ichio Fukasawa
Journal:  Case Rep Obstet Gynecol       Date:  2014-05-13

5.  Effects of gamma radiation on fetal development in mice.

Authors:  Tahere Dehghan; Hossein Mozdarani; Arezoo Khoradmehr; Seyed Mehdi Kalantar
Journal:  Int J Reprod Biomed (Yazd)       Date:  2016-04

6.  Stereotactic body radiation therapy in the treatment of ovarian cancer.

Authors:  Roman O Kowalchuk; Michael R Waters; K Martin Richardson; Kelly Spencer; James M Larner; William P Irvin; Charles R Kersh
Journal:  Radiat Oncol       Date:  2020-05-13       Impact factor: 3.481

7.  Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age.

Authors:  Amy L Winship; Monika Bakai; Urooza Sarma; Seng H Liew; Karla J Hutt
Journal:  Sci Rep       Date:  2018-04-25       Impact factor: 4.379
  7 in total

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