Literature DB >> 18573935

The KQ element, a complex genetic region conferring transferable resistance to carbapenems, aminoglycosides, and fluoroquinolones in Klebsiella pneumoniae.

Louis B Rice1, Lenore L Carias, Rebecca A Hutton, Susan D Rudin, Andrea Endimiani, Robert A Bonomo.   

Abstract

The bla(KPC-3) and qnrB19 determinants of transferable Klebsiella pneumoniae plasmid pLRM24 reside within a complex region consisting of a Tn1331 backbone into which a Tn4401-like element and qnrB19 mobilized by an adjacent ISEcp1 insertion sequence have been inserted. This novel element represents a coalescence of genes conferring multidrug resistance in K. pneumoniae.

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Year:  2008        PMID： 18573935      PMCID： PMC2533511          DOI： 10.1128/AAC.00493-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  Insertion sequence ISEcp1B is involved in expression and mobilization of a bla(CTX-M) beta-lactamase gene.

Authors:  Laurent Poirel; Jean-Winoc Decousser; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

2.  Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa.

Authors:  D M Livermore
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

3.  Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase.

Authors:  Jae Young Kim; Ha Il Jung; Young Jun An; Jung Hun Lee; So Jung Kim; Seok Hoon Jeong; Kye Joon Lee; Pann-Ghill Suh; Heung-Soo Lee; Sang Hee Lee; Sun-Shin Cha
Journal:  Mol Microbiol       Date:  2006-05       Impact factor: 3.501

4.  Prevalence in the United States of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme.

Authors:  Chi Hye Park; Ari Robicsek; George A Jacoby; Daniel Sahm; David C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2006-09-05       Impact factor: 5.191

5.  Mode of transposition and expression of 16S rRNA methyltransferase gene rmtC accompanied by ISEcp1.

Authors:  Jun-ichi Wachino; Kunikazu Yamane; Kouji Kimura; Naohiro Shibata; Satowa Suzuki; Yasuyoshi Ike; Yoshichika Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

6.  DNA sequence analysis of the genetic environment of various blaCTX-M genes.

Authors:  C Eckert; V Gautier; G Arlet
Journal:  J Antimicrob Chemother       Date:  2005-11-16       Impact factor: 5.790

7.  In vitro analysis of ISEcp1B-mediated mobilization of naturally occurring beta-lactamase gene blaCTX-M of Kluyvera ascorbata.

Authors:  Marie-Frédérique Lartigue; Laurent Poirel; Daniel Aubert; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

Review 8.  The worldwide emergence of plasmid-mediated quinolone resistance.

Authors:  Ari Robicsek; George A Jacoby; David C Hooper
Journal:  Lancet Infect Dis       Date:  2006-10       Impact factor: 25.071

9.  Tn5381, a conjugative transposon identifiable as a circular form in Enterococcus faecalis.

Authors:  L B Rice; S H Marshall; L L Carias
Journal:  J Bacteriol       Date:  1992-11       Impact factor: 3.490

10.  DNA sequence analysis of the transposon Tn3: three genes and three sites involved in transposition of Tn3.

Authors:  F Heffron; B J McCarthy; H Ohtsubo; E Ohtsubo
Journal:  Cell       Date:  1979-12       Impact factor: 41.582
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  28 in total

1.  Small plasmids harboring qnrB19: a model for plasmid evolution mediated by site-specific recombination at oriT and Xer sites.

Authors:  Tung Tran; Patricia Andres; Alejandro Petroni; Alfonso Soler-Bistué; Ezequiel Albornoz; Angeles Zorreguieta; Rodrigo Reyes-Lamothe; David J Sherratt; Alejandra Corso; Marcelo E Tolmasky
Journal:  Antimicrob Agents Chemother       Date:  2012-01-30       Impact factor: 5.191

2.  Complete nucleotide sequence of KPC-3-encoding plasmid pKpQIL in the epidemic Klebsiella pneumoniae sequence type 258.

Authors:  Azita Leavitt; Inna Chmelnitsky; Yehuda Carmeli; Shiri Navon-Venezia
Journal:  Antimicrob Agents Chemother       Date:  2010-08-09       Impact factor: 5.191

3.  qnrB19 gene bracketed by IS26 on a 40-kilobase IncR plasmid from an Escherichia coli isolate from a veal calf.

Authors:  Joost Hordijk; Angela B Bosman; Alieda van Essen-Zandbergen; Kees Veldman; Cindy Dierikx; Jaap A Wagenaar; Dik Mevius
Journal:  Antimicrob Agents Chemother       Date:  2010-10-18       Impact factor: 5.191

4.  Complete nucleotide sequence of a blaKPC-harboring IncI2 plasmid and its dissemination in New Jersey and New York hospitals.

Authors:  Liang Chen; Kalyan D Chavda; Nahed Al Laham; Roberto G Melano; Michael R Jacobs; Robert A Bonomo; Barry N Kreiswirth
Journal:  Antimicrob Agents Chemother       Date:  2013-07-29       Impact factor: 5.191

Review 5.  Are we ready for novel detection methods to treat respiratory pathogens in hospital-acquired pneumonia?

Authors:  Andrea Endimiani; Kristine M Hujer; Andrea M Hujer; Sebastian Kurz; Michael R Jacobs; David S Perlin; Robert A Bonomo
Journal:  Clin Infect Dis       Date:  2011-05       Impact factor: 9.079

Review 6.  Plasmid-mediated quinolone resistance.

Authors:  George A Jacoby; Jacob Strahilevitz; David C Hooper
Journal:  Microbiol Spectr       Date:  2014-10

7.  Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil.

Authors:  Leonardo Neves Andrade; Tânia Curiao; Joseane Cristina Ferreira; Juliana Mucedola Longo; Eduardo Carneiro Clímaco; Roberto Martinez; Fernando Bellissimo-Rodrigues; Aníbal Basile-Filho; Marco Antônio Evaristo; Pedro F Del Peloso; Vanessa Bley Ribeiro; Afonso Luis Barth; Milena Cristina Paula; Fernando Baquero; Rafael Cantón; Ana Lúcia da Costa Darini; Teresa M Coque
Journal:  Antimicrob Agents Chemother       Date:  2011-05-16       Impact factor: 5.191

8.  Complex Class 1 Integron Carrying qnrB62 and blaVIM-2 in a Citrobacter freundii Clinical Isolate.

Authors:  Jae Jin Lee; Mi-Na Kim; Kwang Seung Park; Jung Hun Lee; Asad Mustafa Karim; Moonhee Park; Ji Hwan Kim; Sang Hee Lee
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191

9.  Characterization of small ColE-like plasmids mediating widespread dissemination of the qnrB19 gene in commensal enterobacteria.

Authors:  Lucia Pallecchi; Eleonora Riccobono; Samanta Sennati; Antonia Mantella; Filippo Bartalesi; Christian Trigoso; Eduardo Gotuzzo; Alessandro Bartoloni; Gian Maria Rossolini
Journal:  Antimicrob Agents Chemother       Date:  2009-12-14       Impact factor: 5.191

10.  Novel genetic environment of the carbapenem-hydrolyzing beta-lactamase KPC-2 among Enterobacteriaceae in China.

Authors:  Ping Shen; Zeqing Wei; Yan Jiang; Xiaoxing Du; Shujuan Ji; Yunsong Yu; Lanjuan Li
Journal:  Antimicrob Agents Chemother       Date:  2009-07-20       Impact factor: 5.191
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