Literature DB >> 18572891

Self-assembly of Peptide nanotubes in an organic solvent.

M J Krysmann1, V Castelletto, J E McKendrick, L A Clifton, I W Hamley, P J F Harris, S M King.   

Abstract

The self-assembly of a modified fragment of the amyloid beta peptide, based on sequence Abeta(16-20), KLVFF, extended to give AAKLVFF is studied in methanol. Self-assembly into peptide nanotubes is observed, as confirmed by electron microscopy and small-angle X-ray scattering. The secondary structure of the peptide is probed by FTIR and circular dichroism, and UV/visible spectroscopy provides evidence for the important role of aromatic interactions between phenylalanine residues in driving beta-sheet self-assembly. The beta-sheets wrap helically to form the nanotubes, the nanotube wall comprising four wrapped beta-sheets. At higher concentration, the peptide nanotubes form a nematic phase that exhibits spontaneous flow alignment as observed by small-angle neutron scattering.

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Year:  2008        PMID： 18572891     DOI： 10.1021/la800942n

Source DB:  PubMed          Journal:  Langmuir        ISSN： 0743-7463            Impact factor:   3.882


  9 in total

1.  Formation of ordered biomolecular structures by the self-assembly of short peptides.

Authors:  Sivan Yuran; Meital Reches
Journal:  J Vis Exp       Date:  2013-11-21       Impact factor: 1.355

2.  Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation.

Authors:  Clarisa M Torres-Bugeau; César L Ávila; Rita Raisman-Vozari; Dulce Papy-Garcia; Rosangela Itri; Leandro R S Barbosa; Leonardo M Cortez; Valerie L Sim; Rosana N Chehín
Journal:  J Biol Chem       Date:  2011-12-01       Impact factor: 5.157

3.  Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin19-36.

Authors:  William J Howitz; Michał Wierzbicki; Rudy William Cabanela; Cindy Saliba; Ariana Motavalli; Ngoctran Tran; James S Nowick
Journal:  J Am Chem Soc       Date:  2020-09-03       Impact factor: 15.419

Review 4.  Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology.

Authors:  Gang Wei; Zhiqiang Su; Nicholas P Reynolds; Paolo Arosio; Ian W Hamley; Ehud Gazit; Raffaele Mezzenga
Journal:  Chem Soc Rev       Date:  2017-07-31       Impact factor: 54.564

5.  Self-Assembly, Nematic Phase Formation, and Organocatalytic Behavior of a Proline-Functionalized Lipopeptide.

Authors:  Juliane N B D Pelin; Charlotte J C Edwards-Gayle; Valeria Castelletto; Andrea M Aguilar; Wendel A Alves; Jani Seitsonen; Janne Ruokolainen; Ian W Hamley
Journal:  ACS Appl Mater Interfaces       Date:  2020-03-16       Impact factor: 9.229

6.  Two Dimensional Oblique Molecular Packing within a Model Peptide Ribbon Aggregate.

Authors:  Stefan Kuczera; Axel Rüter; Kevin Roger; Ulf Olsson
Journal:  Chemphyschem       Date:  2020-06-23       Impact factor: 3.102

7.  Self-Assembly of Model Amphiphilic Peptides in Nonaqueous Solvents: Changing the Driving Force for Aggregation Does Not Change the Fibril Structure.

Authors:  Alessandra Del Giudice; Axel Rüter; Nicolae Viorel Pavel; Luciano Galantini; Ulf Olsson
Journal:  Langmuir       Date:  2020-07-17       Impact factor: 3.882

8.  Novel dipeptide nanoparticles for effective curcumin delivery.

Authors:  Shadab Alam; Jiban J Panda; Virander S Chauhan
Journal:  Int J Nanomedicine       Date:  2012-08-03

Review 9.  Self-assembling amphiphilic peptides.

Authors:  Ashkan Dehsorkhi; Valeria Castelletto; Ian W Hamley
Journal:  J Pept Sci       Date:  2014-04-13       Impact factor: 1.905
  9 in total

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