Literature DB >> 18571378

Communication abnormalities predict functional outcomes in chronic schizophrenia: differential associations with social and adaptive functions.

Christopher R Bowie1, Philip D Harvey.   

Abstract

Communication abnormalities are hallmark features of schizophrenia. Despite the prevalence and persistence of these symptoms, little is known about their functional implications. In this study, we examined, in a sample of chronically institutionalized schizophrenia patients (N=317), whether two types of communication abnormalities (i.e., verbal underproductivity and disconnected speech) had differential relationships with social and adaptive outcomes. Baseline ratings of verbal underproductivity, disconnected speech, global cognitive performance, and clinical symptoms, were entered into stepwise regression analyses to examine their relationship with 2.5 year social and adaptive outcomes. At baseline, disconnected speech was significantly associated with socially impolite behavior, while verbal underproductivity was associated with social disengagement and impaired friendships. Both types of communication abnormalities were significantly associated with other types of social skills. Verbal underproductivity predicted follow-up social skills, social engagement, and friendships, accounting for more variance than. cognition or symptoms. In contrast to social outcomes, adaptive outcomes were predicted by baseline neurocognition and clinical symptoms, but not communication abnormalities. These findings provide evidence for specific relationships of communication disorder subtypes with diverse impairments in social functions. In this chronically institutionalized sample, communication disorder was a stronger predictor of social, but not adaptive, outcomes than neurocognition or clinical symptoms.

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Year:  2008        PMID: 18571378      PMCID: PMC4104169          DOI: 10.1016/j.schres.2008.05.006

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  45 in total

1.  Neurocognitive and social cognitive correlates of formal thought disorder in schizophrenia patients.

Authors:  Kenneth L Subotnik; Keith H Nuechterlein; Michael F Green; William P Horan; Tasha M Nienow; Joseph Ventura; Annie T Nguyen
Journal:  Schizophr Res       Date:  2006-04-19       Impact factor: 4.939

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3.  Medication effects on referent communication in schizophrenic patients: an evaluation with a structured task.

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Journal:  Brain Lang       Date:  1994-04       Impact factor: 2.381

Review 4.  The specificity of thought disorder to schizophrenia: research methods in their historical perspective.

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5.  Formal thought disorder in schizophrenia: an executive or a semantic deficit?

Authors:  A Barrera; P J McKenna; G E Berrios
Journal:  Psychol Med       Date:  2005-01       Impact factor: 7.723

6.  The association between adaptive and cognitive deficits in geriatric chronic schizophrenic patients.

Authors:  P D Harvey; D Sukhodolsky; M Parrella; L White; M Davidson
Journal:  Schizophr Res       Date:  1997-10-30       Impact factor: 4.939

7.  Thought disorder and psychosocial functioning in schizophrenia: the concurrent and predictive relationships.

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Journal:  J Nerv Ment Dis       Date:  1999-05       Impact factor: 2.254

8.  Thought disorder in schizophrenia is associated with both executive dysfunction and circumscribed impairments in semantic function.

Authors:  John Stirling; Jonathan Hellewell; Andrew Blakey; William Deakin
Journal:  Psychol Med       Date:  2006-01-10       Impact factor: 7.723

9.  Exploration of dimensions of psychopathology in neuroleptic-naïve patients with recent-onset schizophrenia/schizophreniform disorder.

Authors:  John P John; Sumant Khanna; K Thennarasu; Srinivasa Reddy
Journal:  Psychiatry Res       Date:  2003-11-01       Impact factor: 3.222

10.  The MATRICS Consensus Cognitive Battery, part 2: co-norming and standardization.

Authors:  Robert S Kern; Keith H Nuechterlein; Michael F Green; Lyle E Baade; Wayne S Fenton; James M Gold; Richard S E Keefe; Raquelle Mesholam-Gately; Jim Mintz; Larry J Seidman; Ellen Stover; Stephen R Marder
Journal:  Am J Psychiatry       Date:  2008-01-02       Impact factor: 18.112

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  24 in total

1.  Thought, language, and communication deficits and association with everyday functional outcomes among community-dwelling middle-aged and older adults with schizophrenia.

Authors:  Anjana Muralidharan; Anastasia Finch; Christopher R Bowie; Philip D Harvey
Journal:  Schizophr Res       Date:  2017-08-01       Impact factor: 4.939

2.  The cognitive aspect of formal thought disorder and its relationship with global social functioning and the quality of life in schizophrenia.

Authors:  Emre Mutlu; Hatice Abaoğlu; Elif Barışkın; Ş Can Gürel; Aygün Ertuğrul; M Kazım Yazıcı; Esra Akı; A Elif Anıl Yağcıoğlu
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2021-01-17       Impact factor: 4.328

3.  Spared bottom-up but impaired top-down interactive effects during naturalistic language processing in schizophrenia: evidence from the visual-world paradigm.

Authors:  Hugh Rabagliati; Nathaniel Delaney-Busch; Jesse Snedeker; Gina Kuperberg
Journal:  Psychol Med       Date:  2018-08-22       Impact factor: 7.723

Review 4.  The Epidemiology and Associated Phenomenology of Formal Thought Disorder: A Systematic Review.

Authors:  Eric Roche; Lisa Creed; Donagh MacMahon; Daria Brennan; Mary Clarke
Journal:  Schizophr Bull       Date:  2014-09-01       Impact factor: 9.306

5.  Virtual reality assessment of functional capacity in the early course of schizophrenia: Associations with cognitive performance and daily functioning.

Authors:  Joseph Ventura; Tamara Welikson; Arielle Ered; Kenneth L Subotnik; Richard S E Keefe; Gerhard S Hellemann; Keith H Nuechterlein
Journal:  Early Interv Psychiatry       Date:  2019-06-10       Impact factor: 2.732

6.  Testing the hypothesis that formal thought disorders are severe mood disorders.

Authors:  Manuel J Cuesta; Victor Peralta
Journal:  Schizophr Bull       Date:  2011-08-19       Impact factor: 9.306

7.  Computational linguistic analysis applied to a semantic fluency task to measure derailment and tangentiality in schizophrenia.

Authors:  Luca Pauselli; Brooke Halpern; Sean D Cleary; Benson Ku; Michael A Covington; Michael T Compton
Journal:  Psychiatry Res       Date:  2018-02-17       Impact factor: 3.222

8.  The effect of limited cognitive resources on communication disturbances in serious mental illness.

Authors:  Thanh P Le; Gina M Najolia; Kyle S Minor; Alex S Cohen
Journal:  Psychiatry Res       Date:  2016-12-20       Impact factor: 3.222

9.  Language in schizophrenia Part 1: an Introduction.

Authors:  Gina R Kuperberg
Journal:  Lang Linguist Compass       Date:  2010-08

10.  Lexical Characteristics of Emotional Narratives in Schizophrenia: Relationships With Symptoms, Functioning, and Social Cognition.

Authors:  Benjamin Buck; David L Penn
Journal:  J Nerv Ment Dis       Date:  2015-09       Impact factor: 2.254

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