Literature DB >> 18568041

Cytochrome c: functions beyond respiration.

Yong-Ling P Ow1, Douglas R Green, Zhenyue Hao, Tak W Mak.   

Abstract

Cytochrome c is primarily known for its function in the mitochondria as a key participant in the life-supporting function of ATP synthesis. However, when a cell receives an apoptotic stimulus, cytochrome c is released into the cytosol and triggers programmed cell death through apoptosis. The release of cytochrome c and cytochrome-c-mediated apoptosis are controlled by multiple layers of regulation, the most prominent players being members of the B-cell lymphoma protein-2 (BCL2) family. As well as its role in canonical intrinsic apoptosis, cytochrome c amplifies signals that are generated by other apoptotic pathways and participates in certain non-apoptotic functions.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18568041     DOI： 10.1038/nrm2434

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  265 in total

1.  Regulation of the DNA damage response by p53 cofactors.

Authors:  Xiao-Peng Zhang; Feng Liu; Wei Wang
Journal:  Biophys J       Date:  2012-05-15       Impact factor: 4.033

Review 2.  Role of Bcl-2 family proteins and caspases in the regulation of apoptosis.

Authors:  Mohammad Shamsul Ola; Mohd Nawaz; Haseeb Ahsan
Journal:  Mol Cell Biochem       Date:  2011-01-06       Impact factor: 3.396

Review 3.  The engine driving the ship: metabolic steering of cell proliferation and death.

Authors:  Marisa R Buchakjian; Sally Kornbluth
Journal:  Nat Rev Mol Cell Biol       Date:  2010-10       Impact factor: 94.444

4.  CcmI subunit of CcmFHI heme ligation complex functions as an apocytochrome c chaperone during c-type cytochrome maturation.

Authors:  Andreia F Verissimo; Honghui Yang; Xiaomin Wu; Carsten Sanders; Fevzi Daldal
Journal:  J Biol Chem       Date:  2011-09-28       Impact factor: 5.157

5.  Reductive nitrosylation of ferric microperoxidase-11.

Authors:  Paolo Ascenzi; Giovanna De Simone; Diego Sbardella; Massimo Coletta
Journal:  J Biol Inorg Chem       Date:  2018-11-02       Impact factor: 3.358

6.  Capsaicin inhibits cell proliferation by cytochrome c release in gastric cancer cells.

Authors:  Ogunc Meral; Merve Alpay; Gorkem Kismali; Funda Kosova; Dilek Ulker Cakir; Mert Pekcan; Serbulent Yigit; Tevhide Sel
Journal:  Tumour Biol       Date:  2014-03-30

7.  Malate dehydrogenase 2 confers docetaxel resistance via regulations of JNK signaling and oxidative metabolism.

Authors:  Qiong Liu; Chris T Harvey; Hao Geng; Changhui Xue; Vivian Chen; Tomasz M Beer; David Z Qian
Journal:  Prostate       Date:  2013-02-06       Impact factor: 4.104

8.  Cleavage of Bid by executioner caspases mediates feed forward amplification of mitochondrial outer membrane permeabilization during genotoxic stress-induced apoptosis in Jurkat cells.

Authors:  Shary N Shelton; Mary E Shawgo; John D Robertson
Journal:  J Biol Chem       Date:  2009-02-19       Impact factor: 5.157

9.  DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a.

Authors:  Yalu Zhou; Ricardo E Perez; Lei Duan; Carl G Maki
Journal:  Cancer Biol Ther       Date:  2018-03-13       Impact factor: 4.742

10.  N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress.

Authors:  Josie J Gray; Amelia E Zommer; Ron J Bouchard; Nathan Duval; Craig Blackstone; Daniel A Linseman
Journal:  Brain Res       Date:  2012-12-07       Impact factor: 3.252
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.