Anurag Jain1, Jaya Dixit, Dhan Prakash. 1. Department of Periodontics, King George's University of Dental Sciences, Lucknow, India. dranuragjain77@yahoo.co.in
Abstract
OBJECTIVE: The purpose of the present study was to clinically evaluate the efficacy of bovine-derived hydroxyapatite (HA) combined with Cissus quadrangularis (CQ), as compared to bovine-derived hydroxyapatite alone in the treatment of intrabony defects. MATERIALS AND METHODS:Twenty patients with one intrabony defect each were selected for this study. After scaling and root planing, twenty sites were randomly selected to receive either a combination of bovine-derived HA and CQ (test group) or bovine-derived HA alone (control group). Baseline and 6-month surgical reentry measurements were taken and appropriate statistical analysis was performed. RESULTS: Favorable clinical results for both hard and soft tissue measurements were obtained for both groups when compared to baseline (p < 0.001), but there was no statistically significant difference for any of the measured clinical parameters between the two groups. The mean bone fill and percentage bone fill for bovine-derived HA was 2.7 +/- 0.82 mm and 63.2 +/- 17.8%, whereas for composite graft material it was 3.3 +/- 0.82 mm and 69.8 +/- 14.2%. CONCLUSION: Although composite graft material has shown a trend towards better performance, no statistically significant intergroup difference was found. Further studies are needed to establish CQ as a modulator in periodontal regenerative therapy.
RCT Entities:
OBJECTIVE: The purpose of the present study was to clinically evaluate the efficacy of bovine-derived hydroxyapatite (HA) combined with Cissus quadrangularis (CQ), as compared to bovine-derived hydroxyapatite alone in the treatment of intrabony defects. MATERIALS AND METHODS: Twenty patients with one intrabony defect each were selected for this study. After scaling and root planing, twenty sites were randomly selected to receive either a combination of bovine-derived HA and CQ (test group) or bovine-derived HA alone (control group). Baseline and 6-month surgical reentry measurements were taken and appropriate statistical analysis was performed. RESULTS: Favorable clinical results for both hard and soft tissue measurements were obtained for both groups when compared to baseline (p < 0.001), but there was no statistically significant difference for any of the measured clinical parameters between the two groups. The mean bone fill and percentage bone fill for bovine-derived HA was 2.7 +/- 0.82 mm and 63.2 +/- 17.8%, whereas for composite graft material it was 3.3 +/- 0.82 mm and 69.8 +/- 14.2%. CONCLUSION: Although composite graft material has shown a trend towards better performance, no statistically significant intergroup difference was found. Further studies are needed to establish CQ as a modulator in periodontal regenerative therapy.
Authors: Sruthi Sairaman; M S Nivedhitha; Deepti Shrivastava; Meshal Aber Al Onazi; Hmoud Ali Algarni; Mohammed Mustafa; Ali Robaian Alqahtani; Nouf AlQahtani; Kavalipurapu Venkata Teja; Krishnamachari Janani; Rajalakshmanan Eswaramoorthy; M P Sudhakar; Mohammad Khursheed Alam; Kumar Chandan Srivastava Journal: BMC Oral Health Date: 2022-09-05 Impact factor: 3.747
Authors: Bhagath K Potu; Muddanna S Rao; Gopalan K Nampurath; Mallikarjuna R Chamallamudi; Keerthana Prasad; Soubhagya R Nayak; Praveen K Dharmavarapu; Vivekananda Kedage; Kumar M R Bhat Journal: Ups J Med Sci Date: 2009 Impact factor: 2.384