Literature DB >> 18563622

Five-year follow-up of drug utilization for secondary prevention in coronary artery disease.

Sule Apikoglu Rabus1, Fikret V Izzettin, Mesut Sancar, Osman Karakaya, Ramazan Kargin, Cevat Yakut.   

Abstract

OBJECTIVE: Despite the availability of various prevention guidelines on coronary artery disease, secondary prevention practice utilizing aspirin, beta-blockers, angiotensin converting enzyme inhibitors and statins still can be sub-optimal. In this study, we aimed to assess the guideline adherence of secondary prevention prescribing and the continuity of adherence for a 5-year period in a small cohort of patients angiographically diagnosed to have coronary artery disease.
METHOD: In this prospective study, 73 patients who were angiographically diagnosed to have CAD were followed up for 5 years. The baseline demographic and clinical data were collected just before angiography. The baseline drug data were collected at the day of discharge. The fifth year data were taken from the patients via face-to-face consultations or phone interviews.
RESULTS: The 'initial prescribing rate' at discharge was found to be 82% for aspirin, 49% for statins, 44% for ACE inhibitors and 55% for beta-blockers. 'Continuity of prescribing' for 5 years was 45% for aspirin, 26% for statins, 17% for ACE inhibitors and 20% for beta-blockers.
CONCLUSIONS: Besides the sub-optimal prescribing of secondary prevention drugs, absence of continuity of prescribing seems to be a challenging issue in pharmaceutical care of coronary artery disease patients.

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Year:  2008        PMID: 18563622     DOI: 10.1007/s11096-008-9234-3

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  16 in total

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Review 3.  Effectiveness and efficiency of guideline dissemination and implementation strategies.

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6.  Evaluation of the implementation of a local treatment guideline in secondary prevention post-myocardial infarction.

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Authors: 
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Authors:  Cynthia A Jackevicius; Ping Li; Jack V Tu
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10.  The value of inpatient pharmaceutical counselling to elderly patients prior to discharge.

Authors:  S A Al-Rashed; D J Wright; N Roebuck; W Sunter; H Chrystyn
Journal:  Br J Clin Pharmacol       Date:  2002-12       Impact factor: 4.335

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