Literature DB >> 11721672

Evaluation of the implementation of a local treatment guideline in secondary prevention post-myocardial infarction.

F Reid1, B Fossland, A D Flapa, C C Duckelmann, S A Hudson.   

Abstract

OBJECTIVE: To validate and implement an audit tool to assess quality and appropriateness of prescribing. To compare inpatient prescribing of secondary prevention in post myocardial infarction patients before and after introduction of a local treatment guideline.
METHOD: Descriptive, non-experimental retrospective case note review comparing patients treated before and after the implementation of a clinical guideline. MAIN OUTCOME: Comparison of quality of prescribing in two patient groups.
RESULTS: Analysis of Group 1 patients showed that 41% required treatment with an angiotensin converting enzyme inhibitor (ACE-I), and 23% of those did not receive treatment, 20% of patients on ACE-I received sub-therapeutic doses. Seventy-two per cent of patients required treatment with a statin and 22% of those did not receive a statin. Comparison of the treatment of Group 2 showed that, of 53 patients (50% of Group 2) requiring an ACE-I, 100% received it, although 15% received sub-therapeutic doses. Of 69 patients (64% of Group 2) requiring treatment with a statin 96% were prescribed a statin. Improvements in prescribing of beta-Blockers, ACE-I and statins were statistically significant.
CONCLUSIONS: Prescribing improved significantly for beta-Blockers, ACE-I and statins after guideline introduction with anticipated benefits to patient outcomes.

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Year:  2001        PMID: 11721672     DOI: 10.1023/a:1012231814131

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  1 in total

1.  Five-year follow-up of drug utilization for secondary prevention in coronary artery disease.

Authors:  Sule Apikoglu Rabus; Fikret V Izzettin; Mesut Sancar; Osman Karakaya; Ramazan Kargin; Cevat Yakut
Journal:  Pharm World Sci       Date:  2008-06-19
  1 in total

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