Literature DB >> 18563340

Expression of apoptosis related protein in skin lesions of lichen planus and its implication.

Xu'e Chen1, Yan Wu, Jiawen Li, Zhixiang Liu, Qing Yue, Houjun Liu.   

Abstract

In order to investigate the role of Caspase-3 and Bax in the pathogenesis of lichen planus, immunohistochemistry was used to detect the expression of Caspase-3 and Bax in skin lesions of the patients with lichen planus and skin tissues of normal subjects. The results showed that positive rate of Caspase-3 and Bax expression in lichen planus were significantly higher than that in normal skins (both P<0.05). Meanwhile, there was a obvious correlation between the increase of Caspase-3 and that of Bax in lichen planus. The expression of Caspase-3 and Bax might play an important role in the development of lichen planus.

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Year:  2008        PMID： 18563340     DOI： 10.1007/s11596-008-0328-x

Source DB:  PubMed          Journal:  J Huazhong Univ Sci Technolog Med Sci        ISSN： 1672-0733


  9 in total

Review 1.  Oral lichen planus.

Authors:  P B Sugerman; N W Savage; X Zhou; L J Walsh; M Bigby
Journal:  Clin Dermatol       Date:  2000 Sep-Oct       Impact factor: 3.541

2.  Matrix metalloproteinase gene expression in oral lichen planus: erosive vs. reticular forms.

Authors:  N Mazzarella; F Femiano; F Gombos; A De Rosa; M Giuliano
Journal:  J Eur Acad Dermatol Venereol       Date:  2006-09       Impact factor: 6.166

3.  Apoptosis in oral lichen planus.

Authors:  E Neppelberg; A C Johannessen; R Jonsson
Journal:  Eur J Oral Sci       Date:  2001-10       Impact factor: 2.612

4.  Expression of apoptotic signaling proteins in leukoplakia and oral lichen planus: quantitative and topographical studies.

Authors:  N Tanda; S Mori; K Saito; K Ikawa; S Sakamoto
Journal:  J Oral Pathol Med       Date:  2000-09       Impact factor: 4.253

5.  Caspase activation during spontaneous and radiation-induced apoptosis in the murine intestine.

Authors:  E Marshman; P D Ottewell; C S Potten; A J Watson
Journal:  J Pathol       Date:  2001-10       Impact factor: 7.996

6.  NF-kappaB expression in oral and cutaneous lichen planus.

Authors:  Amerigo Santoro; Alessandra Majorana; Elena Bardellini; Silvana Festa; Pierluigi Sapelli; Fabio Facchetti
Journal:  J Pathol       Date:  2003-11       Impact factor: 7.996

7.  Expression of caspase-3 and structural changes associated with apoptotic cell death of keratinocytes in oral lichen planus.

Authors:  S I Tobón-Arroyave; F A Villegas-Acosta; S M Ruiz-Restrepo; B Vieco-Durán; M Restrepo-Misas; M L Londoño-López
Journal:  Oral Dis       Date:  2004-05       Impact factor: 3.511

8.  The expression of TNF-alpha and ICAM-1 in lesions of lichen planus and its implication.

Authors:  Xu'e Chen; Zhixiang Liu; Qing Yue
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2007-12

Review 9.  The pathogenesis of oral lichen planus.

Authors:  P B Sugerman; N W Savage; L J Walsh; Z Z Zhao; X J Zhou; A Khan; G J Seymour; M Bigby
Journal:  Crit Rev Oral Biol Med       Date:  2002
  9 in total
  1 in total

1.  Assessment of bax and bcl-2 immunoexpression in patients with oral lichen planus and oral squamous cell carcinoma.

Authors:  Shima Nafarzadeh; Sina Jafari; Ali Bijani
Journal:  Int J Mol Cell Med       Date:  2013
  1 in total

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