Literature DB >> 18560951

[Surgical treatment options in laryngeal and hypopharyngeal cancer].

Hans E Eckel1, Ursula Schröder, Markus Jungehülsing, Orlando Guntinas-Lichius, Michael Markitz, Wolfgang Raunik.   

Abstract

In Austria, around ten new cases of laryngeal cancer can currently be expected per 100.000 persons each year whereas three out of 100.000 men develope hypopharyngeal cancer. Among women, the incidence in both types of carcinoma is lower by a factor of around 5. All in all, the rate of new cases seems to have been constant or to have slightly decreased in the last few years. Approximately 70% of all laryngeal cancer are glottic cancer, that is to say originating from the vocal cords. About 30% are supraglottic tumours, true subglottic cancers are very rare. The majority of hypopharyngeal tumours originate from the piriform sinuses. Vocal cord tumours lead to a typical symptom that can be early detected: hoarseness. Thus, voice problems in adults that persist for several weeks should therefore always checked by laryngoscopy. This leads to there being a real possibility of early diagnosis of laryngeal cancer, which means that today, approximately 60% of all laryngeal tumours can be diagnosed in stage I or II according to UICC or as intraepithelial lesions (former carcinoma in situ). In glottic cancer about 75% are diagnosed in these early stages, whereas in supraglottic tumours the rate is only about 30% and in hypopharyngeal cancer it is less then 15%. Surgery, radiation therapy, chemo- or immunotherapy are the principal types of oncological treatments currently available. The following conditions generally need to be met for curative surgical treatment options: Local tumour, no systemic metastasis Tumour has to be resectable in healthy margins mortality/morbidity Surgery must not lead to unreasonable mutilation Lack of other therapeutic alternatives having an equal or lesser impact In the following pages, indications for the surgical treatment of laryngeal and hypopharyngeal cancer will be discussed and the results of surgical therapy will be summarised briefly.

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Year:  2008        PMID: 18560951     DOI: 10.1007/s10354-008-0530-2

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  26 in total

1.  Complications of suspension laryngoscopy.

Authors:  Jens Peter Klussmann; Robert Knoedgen; Claus Wittekindt; Michael Damm; Hans Edmund Eckel
Journal:  Ann Otol Rhinol Laryngol       Date:  2002-11       Impact factor: 1.547

Review 2.  Voice-related quality of life in T1 glottic cancer: irradiation versus endoscopic excision.

Authors:  Seth M Cohen; C Gaelyn Garrett; William D Dupont; Robert H Ossoff; Mark S Courey
Journal:  Ann Otol Rhinol Laryngol       Date:  2006-08       Impact factor: 1.547

Review 3.  [Current value of open-preservation surgery with special emphasis given to the supracricoid laryngectomy].

Authors:  U Schröder
Journal:  Laryngorhinootologie       Date:  2007-07       Impact factor: 1.057

4.  [Quality of life and voice handicap of laryngectomees using tracheoesophageal substitute voice].

Authors:  M Schuster; H Toy; J Lohscheller; U Eysholdt; F Rosanowski
Journal:  Laryngorhinootologie       Date:  2005-02       Impact factor: 1.057

5.  Local recurrences following transoral laser surgery for early glottic carcinoma: frequency, management, and outcome.

Authors:  H E Eckel
Journal:  Ann Otol Rhinol Laryngol       Date:  2001-01       Impact factor: 1.547

6.  [Treatment of carcinoma of the piriform sinus].

Authors:  O Kleinsasser; H Glanz; T Kimmich
Journal:  HNO       Date:  1989-11       Impact factor: 1.284

7.  Endoscopic CO2 laser surgery for early glottic cancer in patients who are candidates for radiotherapy: results of a prospective nonrandomized study.

Authors:  Mohssen Ansarin; Michal Zabrodsky; Livia Bianchi; Giuseppe Renne; Antonella Tosoni; Luca Calabrese; Paola Tredici; Barbara A Jereczek-Fossa; Roberto Orecchia; Fausto Chiesa
Journal:  Head Neck       Date:  2006-02       Impact factor: 3.147

8.  Total laryngectomy and postoperative radiotherapy for T4 laryngeal cancer: a 14-year review.

Authors:  Federico L Ampil; Cherie Ann O Nathan; Gloria Caldito; Timothy F Lian; Robert F Aarstad; R Murty Krishnamsetty
Journal:  Am J Otolaryngol       Date:  2004 Mar-Apr       Impact factor: 1.808

9.  [Cricohyoidopexy (CHP) and Cricohyoidoepiglottopexy (CHEP). Indication, complications, functional und oncological results].

Authors:  U Schröder; M Jungehülsing; J P Klussmann; H E Eckel
Journal:  HNO       Date:  2003-01       Impact factor: 1.284

10.  Challenging a dogma--surgery yields superior long-term results for T1a squamous cell carcinoma of the glottic larynx compared to radiotherapy.

Authors:  D Thurnher; B M Erovic; F Frommlet; W Brannath; K Ehrenberger; B Jansen; E Selzer; M C Grasl
Journal:  Eur J Surg Oncol       Date:  2007-08-08       Impact factor: 4.424

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  5 in total

1.  [Recent advances in the treatment of laryngeal and hypopharyngeal carcinoma].

Authors:  H E Eckel
Journal:  HNO       Date:  2012-01       Impact factor: 1.284

2.  Incidence and localization of abnormal mucosa findings in patients consulting ENT outpatient clinics and data analysis of a cancer registry.

Authors:  J Löhler; A O H Gerstner; F Bootz; L E Walther
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-10-10       Impact factor: 2.503

3.  [Prevalence of abnormal mucosal findings in patients in HNO practices].

Authors:  J Löhler; A O H Gerstner; F Bootz; H Heinritz; A Fryen; G Fryen; N Holstein; A Lingg; J Kleeberg; W Langhoff; G Rösch; A Hanisch; E Schneeberg; D Heinrich; L E Walther
Journal:  HNO       Date:  2012-03       Impact factor: 1.284

4.  Predictors of thyroid gland involvement in hypopharyngeal squamous cell carcinoma.

Authors:  Jae Won Chang; Yoon Woo Koh; Woong Youn Chung; Soon Won Hong; Eun Chang Choi
Journal:  Yonsei Med J       Date:  2015-05       Impact factor: 2.759

5.  A modified false vocal fold flap for functional reconstruction after frontolateral partial laryngectomy: a comparison with conventional open resection and laser cordectomy.

Authors:  Kai J Lorenz; Roland Kohnle; Heinz Maier
Journal:  GMS Interdiscip Plast Reconstr Surg DGPW       Date:  2013-10-23
  5 in total

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