OBJECTIVES: We examined the association between childhood socioeconomic position and incidence of type 2 diabetes and the effects of gender and adult body mass index (BMI). METHODS: We studied 5913 participants in the Alameda County Study from 1965 to 1999 who were diabetes free at baseline (1965). Cox proportional hazards models estimated diabetes risk associated with childhood socioeconomic position and combined childhood socioeconomic position-adult BMI categories in pooled and gender-stratified samples. Demographic confounders and potential pathway components (physical inactivity, smoking, alcohol consumption, hypertension, depression, health care access) were included as covariates. RESULTS: Low childhood socioeconomic position was associated with excess diabetes risk, especially among women. Race and body composition accounted for some of this excess risk. The association between childhood socioeconomic position and diabetes incidence differed by adult BMI category in the pooled and women-only groups. Adjustment for race and behaviors attenuated the risk attributable to low childhood socioeconomic position among the obese group only. CONCLUSIONS: Childhood socioeconomic position was a robust predictor of incident diabetes, especially among women. A cumulative risk effect was observed for both childhood socioeconomic position and adult BMI, especially among women.
OBJECTIVES: We examined the association between childhood socioeconomic position and incidence of type 2 diabetes and the effects of gender and adult body mass index (BMI). METHODS: We studied 5913 participants in the Alameda County Study from 1965 to 1999 who were diabetes free at baseline (1965). Cox proportional hazards models estimated diabetes risk associated with childhood socioeconomic position and combined childhood socioeconomic position-adult BMI categories in pooled and gender-stratified samples. Demographic confounders and potential pathway components (physical inactivity, smoking, alcohol consumption, hypertension, depression, health care access) were included as covariates. RESULTS: Low childhood socioeconomic position was associated with excess diabetes risk, especially among women. Race and body composition accounted for some of this excess risk. The association between childhood socioeconomic position and diabetes incidence differed by adult BMI category in the pooled and women-only groups. Adjustment for race and behaviors attenuated the risk attributable to low childhood socioeconomic position among the obese group only. CONCLUSIONS: Childhood socioeconomic position was a robust predictor of incident diabetes, especially among women. A cumulative risk effect was observed for both childhood socioeconomic position and adult BMI, especially among women.
Authors: Calpurnyia B Roberts; David J Couper; Patricia P Chang; Sherman A James; Wayne D Rosamond; Gerardo Heiss Journal: Am J Epidemiol Date: 2010-08-08 Impact factor: 4.897
Authors: Jennifer Karas Montez; Joyce T Bromberger; Siobán D Harlow; Howard M Kravitz; Karen A Matthews Journal: J Gerontol B Psychol Sci Soc Sci Date: 2016-02-28 Impact factor: 4.077
Authors: Richard S Liu; Allison E Aiello; Fiona K Mensah; Constantine E Gasser; Kuna Rueb; Billie Cordell; Markus Juonala; Melissa Wake; David P Burgner Journal: J Epidemiol Community Health Date: 2017-05-10 Impact factor: 3.710
Authors: J Bradley Williams; Diana Pang; Bertha Delgado; Masha Kocherginsky; Maria Tretiakova; Thomas Krausz; Deng Pan; Jane He; Martha K McClintock; Suzanne D Conzen Journal: Cancer Prev Res (Phila) Date: 2009-09-29