Literature DB >> 18553895

Charge dependence of ligand release and monolayer stability of gold nanoparticles by biogenic thiols.

Apiwat Chompoosor1, Gang Han, Vincent M Rotello.   

Abstract

The effect of surface charge on the stability of gold nanoparticles (AuNPs) to the biogenic thiols glutathione (GSH), dihydrolipoic acid (DHLA), and cysteine was quantified. It was observed that the rate of release of fluorescein-tagged ligand was determined by the surface charge of the AuNPs, with cationic particles much more labile than anionic analogues. This ability to tune stability is significant for the design of both delivery vehicles and intracellular probes.

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Year:  2008        PMID： 18553895     DOI： 10.1021/bc8000694

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  17 in total

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