Literature DB >> 18551277

The location-specific healing response of damaged articular cartilage after ACL reconstruction: short-term follow-up.

Norimasa Nakamura1, Shuji Horibe, Yukiyoshi Toritsuka, Tomoki Mitsuoka, Takashi Natsu-ume, Kenji Yoneda, Masayuki Hamada, Yoshinari Tanaka, Richard S Boorman, Hideki Yoshikawa, Konsei Shino.   

Abstract

Although many different interventions have been proposed for treating cartilage lesions at the time of ACL reconstruction, the normal healing response of these injuries has not been well documented. To address this point, we compared the arthroscopic status of chondral lesions at the time of ACL reconstruction with that obtained at second-look arthroscopy. We hypothesized that there might be a location-specific difference in the healing response of damaged articular cartilage. Between September 1998 and March 2000, 383 patients underwent arthroscopically-assisted hamstring ACL reconstruction without any intervention to the articular cartilage. Among these patients, 84 patients underwent second-look arthroscopy (ranging from 6 to 52 months following initial surgery) and make up the population of the present study. Chondral injuries, left untreated at ACL reconstruction, were arthroscopically evaluated using the Outerbridge classification, and were again evaluated at second-look arthroscopy. At second-look arthroscopy, there was significant recovery of chondral lesions by Outerbridge grading on both the medial and lateral femoral condyles. Among the recovered chondral lesions, 69% of cases of the medial femoral condyle, 88% of cases of the lateral femoral condyle were partial thickness injuries (grade I and II). Conversely, there was no significant recovery of chondral lesions observed at the patello-femoral joint or tibial plateaus. Our study revealed that there was a location-specific difference in the natural healing response of chondral injury. Untreated cartilage lesions on the femoral condlyes had a superior healing response compared to those on the tibial plateaus, and in the patello-femoral joint.

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Year:  2008        PMID: 18551277     DOI: 10.1007/s00167-008-0565-3

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  33 in total

1.  Reproducibility and reliability of the outerbridge classification for grading chondral lesions of the knee arthroscopically.

Authors:  Michelle L Cameron; Karen K Briggs; J Richard Steadman
Journal:  Am J Sports Med       Date:  2003 Jan-Feb       Impact factor: 6.202

2.  The reactions of injured human articular cartilage.

Authors:  J W LANDELLS
Journal:  J Bone Joint Surg Br       Date:  1957-08

3.  The role of the synovium in repairing cartilage defects.

Authors:  Ayato Miyamoto; Masataka Deie; Takuma Yamasaki; Atsuo Nakamae; Rikuo Shinomiya; Nobuo Adachi; Mitsuo Ochi
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2007-02-06       Impact factor: 4.342

4.  Process of repair of articular cartilage demonstrated by histology and autoradiography with tritiated thymidine.

Authors:  A F DePalma; C D McKeever; D K Subin
Journal:  Clin Orthop Relat Res       Date:  1966 Sep-Oct       Impact factor: 4.176

5.  Arthroscopy in acute traumatic hemarthrosis of the knee. Incidence of anterior cruciate tears and other injuries.

Authors:  F R Noyes; R W Bassett; E S Grood; D L Butler
Journal:  J Bone Joint Surg Am       Date:  1980-07       Impact factor: 5.284

6.  Multipotent mesenchymal stem cells from adult human synovial membrane.

Authors:  C De Bari; F Dell'Accio; P Tylzanowski; F P Luyten
Journal:  Arthritis Rheum       Date:  2001-08

Review 7.  Articular cartilage repair.

Authors:  A P Newman
Journal:  Am J Sports Med       Date:  1998 Mar-Apr       Impact factor: 6.202

8.  Two- to 9-year outcome after autologous chondrocyte transplantation of the knee.

Authors:  L Peterson; T Minas; M Brittberg; A Nilsson; E Sjögren-Jansson; A Lindahl
Journal:  Clin Orthop Relat Res       Date:  2000-05       Impact factor: 4.176

Review 9.  Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects.

Authors:  E B Hunziker
Journal:  Osteoarthritis Cartilage       Date:  2002-06       Impact factor: 6.576

10.  Isolated posterior cruciate ligament injuries in athletes.

Authors:  P J Fowler; S S Messieh
Journal:  Am J Sports Med       Date:  1987 Nov-Dec       Impact factor: 6.202

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  7 in total

Review 1.  Do cartilage lesions affect the clinical outcome of anterior cruciate ligament reconstruction? A systematic review.

Authors:  Giuseppe Filardo; Francesca de Caro; Luca Andriolo; Elizaveta Kon; Stefano Zaffagnini; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-04-04       Impact factor: 4.342

2.  No evidence for the most appropriate postoperative rehabilitation protocol following anterior cruciate ligament reconstruction with concomitant articular cartilage lesions: a systematic review.

Authors:  Ciaran Thrush; Tabitha J Porter; Brian M Devitt
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-03-06       Impact factor: 4.342

Review 3.  Anterior cruciate ligament tears: conservative or surgical treatment? A critical review of the literature.

Authors:  Philippe Delincé; Dior Ghafil
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-07-20       Impact factor: 4.342

Review 4.  Regeneration of articular cartilage of the knee.

Authors:  E Carlos Rodriguez-Merchan
Journal:  Rheumatol Int       Date:  2012-12-23       Impact factor: 2.631

5.  Biomechanical considerations in the pathogenesis of osteoarthritis of the knee.

Authors:  Andras Heijink; Andreas H Gomoll; Henning Madry; Matej Drobnič; Giuseppe Filardo; João Espregueira-Mendes; C Niek Van Dijk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-12-16       Impact factor: 4.342

6.  Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?

Authors:  John Garcia; Helen S McCarthy; Jan Herman Kuiper; James Melrose; Sally Roberts
Journal:  Biomolecules       Date:  2021-01-13

7.  Second-look arthroscopy after double-bundle posterior cruciate ligament reconstruction: Effect of patient age.

Authors:  Yuta Tachibana; Yoshinari Tanaka; Kinugasa Kazutaka; Shuji Horibe
Journal:  Asia Pac J Sports Med Arthrosc Rehabil Technol       Date:  2021-10-14
  7 in total

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