Literature DB >> 18547214

Maximum effect of triptans in migraine? A comment.

P Tfelt-Hansen1.   

Abstract

The efficacy of triptans in the treatment of migraine was recently contested. How high is then the maximum effect of a triptan? After subcutaneous naratriptan 10 mg a 88% pain-free response was observed. This result was obtained despite the fact that more half of the patients had a migraine duration of > 4 h. These results indicate that subcutaneous naratriptan in a high dose can overcome central sensitization that occurs in migraine attacks.

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Year:  2008        PMID: 18547214     DOI: 10.1111/j.1468-2982.2007.01415.x

Source DB:  PubMed          Journal:  Cephalalgia        ISSN: 0333-1024            Impact factor:   6.292


  7 in total

Review 1.  Taking the negative view of current migraine treatments: the unmet needs.

Authors:  Peer Tfelt-Hansen; Jes Olesen
Journal:  CNS Drugs       Date:  2012-05-01       Impact factor: 5.749

Review 2.  Does sumatriptan cross the blood-brain barrier in animals and man?

Authors:  Peer Carsten Tfelt-Hansen
Journal:  J Headache Pain       Date:  2009-12-10       Impact factor: 7.277

3.  Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial.

Authors:  Kenneth A Holroyd; Constance K Cottrell; Francis J O'Donnell; Gary E Cordingley; Jana B Drew; Bruce W Carlson; Lina Himawan
Journal:  BMJ       Date:  2010-09-29

Review 4.  Cutaneous Allodynia in Migraine: A Narrative Review.

Authors:  Ane Mínguez-Olaondo; Sonia Quintas; Noemí Morollón Sánchez-Mateos; Alba López-Bravo; Marta Vila-Pueyo; Vesselina Grozeva; Robert Belvís; Sonia Santos-Lasaosa; Pablo Irimia
Journal:  Front Neurol       Date:  2022-01-21       Impact factor: 4.003

Review 5.  Parenteral vs. oral sumatriptan and naratriptan: plasma levels and efficacy in migraine. a comment.

Authors:  Peer Tfelt-Hansen
Journal:  J Headache Pain       Date:  2007-10-23       Impact factor: 7.277

6.  Is there an inherent limit to the efficacy of calcitonin gene-related peptide receptor antagonists in the acute treatment of migraine? A comment.

Authors:  Peer C Tfelt-Hansen
Journal:  J Headache Pain       Date:  2009-09-25       Impact factor: 7.277

Review 7.  Pharmacogenomics and migraine: possible implications.

Authors:  Peer Tfelt-Hansen; Kim Brøsen
Journal:  J Headache Pain       Date:  2008-01-24       Impact factor: 7.277

  7 in total

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