Literature DB >> 18546010

Selective retina therapy (SRT) of chronic subfoveal fluid after surgery of rhegmatogenous retinal detachment: three case reports.

Stefan Koinzer1, Hanno Elsner, Carsten Klatt, Erk Pörksen, Ralf Brinkmann, Reginald Birngruber, Johann Roider.   

Abstract

BACKGROUND: Shallow subfoveal fluid accumulation after successful surgery for retinal detachment can be the reason for compromised visual acuity. To date, therapeutical options to tackle this problem have not been established. Selective retina therapy (SRT) is a new laser technology that uses a train of mus-laser pulses to selectively damage retinal pigment epithelial (RPE) cells while sparing retinal structures.
METHODS: We treated three patients with chronic subfoveal fluid accumulation after retinal detachment surgery. The median period between retinal surgery and SRT treatment was 7 months. For SRT, we used a prototype frequency-doubled, Q-switched Nd:YLF laser (lambda = 527 nm). Each laser exposition contained 30 pulses (t = 1,7 micros, 100 Hz, E = 100-400 microJ). Two of the three patients were treated subfoveally. OCT III (optical coherence tomography) examinations were performed to evaluate changes in subretinal fluid accumulation.
RESULTS: In all three patients, we observed complete resolution of subfoveal fluid within 1-5 months. Follow-up has been 16 months to 2 years. Visual acuity improved in all patients. In one patient, cystoid macular edema developed 3 months after treatment. Additional SRT treatments were not necessary.
CONCLUSION: SRT is a safe treatment. Visual acuity improved after SRT, even in subfoveal irradiations. SRT is an option to support subretinal fluid reabsorption. In this situation where no other therapeutical options are established, SRT may be a beneficial treatment for chronic subfoveal fluid accumulation after retinal detachment surgery.

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Year:  2008        PMID: 18546010     DOI: 10.1007/s00417-008-0860-1

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  21 in total

1.  Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen.

Authors:  R Brinkmann; G Hüttmann; J Rögener; J Roider; R Birngruber; C P Lin
Journal:  Lasers Surg Med       Date:  2000       Impact factor: 4.025

2.  Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam.

Authors:  Ralf Brinkmann; Norbert Koop; Mustafa Ozdemir; Clemens Alt; Georg Schüle; Charles P Lin; Reginald Birngruber
Journal:  Lasers Surg Med       Date:  2003       Impact factor: 4.025

3.  Selective retina therapy in patients with central serous chorioretinopathy.

Authors:  H Elsner; E Pörksen; C Klatt; A Bunse; D Theisen-Kunde; R Brinkmann; R Birngruber; H Laqua; J Roider
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-12       Impact factor: 3.117

4.  Subthreshold (retinal pigment epithelium) photocoagulation in macular diseases: a pilot study.

Authors:  J Roider; R Brinkmann; C Wirbelauer; H Laqua; R Birngruber
Journal:  Br J Ophthalmol       Date:  2000-01       Impact factor: 4.638

5.  Histopathologic study of the effect of retinal detachment surgery on 49 eyes obtained post mortem.

Authors:  D J Wilson; W R Green
Journal:  Am J Ophthalmol       Date:  1987-02-15       Impact factor: 5.258

6.  Optical coherence tomography in the evaluation of incomplete visual acuity recovery after macula-off retinal detachments.

Authors:  Thomas J Wolfensberger; Michel Gonvers
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2002-02       Impact factor: 3.117

7.  Persistent foveal retinal detachment after successful rhegmatogenous retinal detachment surgery.

Authors:  Norikazu Hagimura; Tomohiro Iida; Katsuya Suto; Shoji Kishi
Journal:  Am J Ophthalmol       Date:  2002-04       Impact factor: 5.258

8.  Ultrahigh-resolution optical coherence tomography in patients with decreased visual acuity after retinal detachment repair.

Authors:  Lisa S Schocket; Andre J Witkin; James G Fujimoto; Tony H Ko; Joel S Schuman; Adam H Rogers; Caroline Baumal; Elias Reichel; Jay S Duker
Journal:  Ophthalmology       Date:  2006-04       Impact factor: 12.079

9.  Experimental serous retinal detachment and focal pigment epithelial damage.

Authors:  A Negi; M F Marmor
Journal:  Arch Ophthalmol       Date:  1984-03

10.  Tomographic image and visual recovery of acute macula-off rhegmatogenous retinal detachment.

Authors:  Takayuki Baba; Akira Hirose; Muka Moriyama; Manabu Mochizuki
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-03-02       Impact factor: 3.117

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  12 in total

1.  Persistent subfoveolar fluid following retinal detachment surgery: an SD-OCT guided study on the incidence, aetiological associations, and natural history.

Authors:  J J L Tee; M Veckeneer; D A Laidlaw
Journal:  Eye (Lond)       Date:  2016-01-08       Impact factor: 3.775

2.  Retinal sensitivity after selective retina therapy (SRT) on patients with central serous chorioretinopathy.

Authors:  Ayako Yasui; Manabu Yamamoto; Kumiko Hirayama; Kunihiko Shiraki; Dirk Theisen-Kunde; Ralf Brinkmann; Yoko Miura; Takeya Kohno
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-08-06       Impact factor: 3.117

3.  Comparison of the neuroinflammatory responses to selective retina therapy and continuous-wave laser photocoagulation in mouse eyes.

Authors:  Jung Woo Han; Juhye Choi; Young Shin Kim; Jina Kim; Ralf Brinkmann; Jungmook Lyu; Tae Kwann Park
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-01-10       Impact factor: 3.117

Review 4.  Persistent subretinal fluid after surgery for rhegmatogenous retinal detachment: hypothesis and review.

Authors:  M Veckeneer; L Derycke; E W Lindstedt; J van Meurs; M Cornelissen; M Bracke; E Van Aken
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-01-11       Impact factor: 3.117

5.  Safety and efficacy of selective retina therapy (SRT) for the treatment of diabetic macular edema in Korean patients.

Authors:  Young Gun Park; Jae Ryun Kim; Seungbum Kang; Eric Seifert; Dirk Theisen-Kunde; Ralf Brinkmann; Young-Jung Roh
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-01-23       Impact factor: 3.117

6.  Temperature-Controlled Retinal Photocoagulation Reliably Generates Uniform Subvisible, Mild, or Moderate Lesions.

Authors:  Stefan Koinzer; Alexander Baade; Kerstin Schlott; Carola Hesse; Amke Caliebe; Johann Roider; Ralf Brinkmann
Journal:  Transl Vis Sci Technol       Date:  2015-10-06       Impact factor: 3.283

7.  Comprehensive detection, grading, and growth behavior evaluation of subthreshold and low intensity photocoagulation lesions by optical coherence tomographic and infrared image analysis.

Authors:  Stefan Koinzer; Amke Caliebe; Lea Portz; Mark Saeger; Yoko Miura; Kerstin Schlott; Ralf Brinkmann; Johann Roider
Journal:  Biomed Res Int       Date:  2014-05-12       Impact factor: 3.411

Review 8.  Laser-based strategies to treat diabetic macular edema: history and new promising therapies.

Authors:  Young Gun Park; Eun Yeong Kim; Young Jung Roh
Journal:  J Ophthalmol       Date:  2014-09-22       Impact factor: 1.909

9.  A Comparative Study of Retinal Function in Rabbits after Panretinal Selective Retina Therapy versus Conventional Panretinal Photocoagulation.

Authors:  Young Gun Park; Seungbum Kang; Ralf Brinkmann; Young-Jung Roh
Journal:  J Ophthalmol       Date:  2015-10-07       Impact factor: 1.909

10.  Selective Retina Therapy in Patients With Chronic Central Serous Chorioretinopathy: A Pilot Study.

Authors:  Seungbum Kang; Young Gun Park; Jae Ryun Kim; Eric Seifert; Dirk Theisen-Kunde; Ralf Brinkmann; Young Jung Roh
Journal:  Medicine (Baltimore)       Date:  2016-01       Impact factor: 1.817

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