| Literature DB >> 18545505 |
Vladimir Hovhannisyan1, Wen Lo, Chieh Hu, Shean-Jen Chen, Chen Yuan Dong.
Abstract
In this work, we investigate the non-ablative, non-thermal photo-modification of collagen fibers by femtosecond Ti:Sa laser. The effect was induced and simultaneously registered during the repetitive laser scanning of type I collagen (rat tail and bovine Achilles' tendon), and bovine cornea. An irreversible increase in two-photon autofluorescence and a decrease in second harmonic generation intensities were associated with the collagen femtosecond laser photo-modification. Confocal spectral imaging revealed the formation of new fluorescent species. Controllable nonlinear photo-modification of collagen fibers and bovine cornea with approximately 2 microm spatial resolution was demonstrated.Entities:
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Year: 2008 PMID: 18545505 DOI: 10.1364/oe.16.007958
Source DB: PubMed Journal: Opt Express ISSN: 1094-4087 Impact factor: 3.894