Literature DB >> 18536723

Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation.

Carlos Martinez-Fleites1, Matthew S Macauley, Yuan He, David L Shen, David J Vocadlo, Gideon J Davies.   

Abstract

N-Acetylglucosamine (O-GlcNAc) modification of proteins provides a mechanism for the control of diverse cellular processes through a dynamic interplay with phosphorylation. UDP-GlcNAc:polypeptidyl transferase (OGT) catalyzes O-GlcNAc addition. The structure of an intact OGT homolog and kinetic analysis of human OGT variants reveal a contiguous superhelical groove that directs substrates to the active site.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18536723     DOI： 10.1038/nsmb.1443

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  57 in total

Review 1.  The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.

Authors:  Natasha E Zachara
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-01-27       Impact factor: 4.733

2.  Insights into O-linked N-acetylglucosamine ([0-9]O-GlcNAc) processing and dynamics through kinetic analysis of O-GlcNAc transferase and O-GlcNAcase activity on protein substrates.

Authors:  David L Shen; Tracey M Gloster; Scott A Yuzwa; David J Vocadlo
Journal:  J Biol Chem       Date:  2012-02-06       Impact factor: 5.157

Review 3.  Nutrient regulation of signaling and transcription.

Authors:  Gerald W Hart
Journal:  J Biol Chem       Date:  2019-01-09       Impact factor: 5.157

Review 4.  Too sweet to resist: Control of immune cell function by O-GlcNAcylation.

Authors:  Tristan de Jesus; Sudhanshu Shukla; Parameswaran Ramakrishnan
Journal:  Cell Immunol       Date:  2018-06-02       Impact factor: 4.868

5.  Cytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NX(S/T) consensus sequence.

Authors:  Flavio Schwarz; Yao-Yun Fan; Mario Schubert; Markus Aebi
Journal:  J Biol Chem       Date:  2011-08-18       Impact factor: 5.157

Review 6.  The making of a sweet modification: structure and function of O-GlcNAc transferase.

Authors:  John Janetzko; Suzanne Walker
Journal:  J Biol Chem       Date:  2014-10-21       Impact factor: 5.157

Review 7.  Glycosyltransferase-mediated Sweet Modification in Oral Streptococci.

Authors:  F Zhu; H Zhang; H Wu
Journal:  J Dent Res       Date:  2015-03-09       Impact factor: 6.116

Review 8.  O-GlcNAc and the cardiovascular system.

Authors:  Sujith Dassanayaka; Steven P Jones
Journal:  Pharmacol Ther       Date:  2013-11-25       Impact factor: 12.310

Review 9.  O-GlcNAc protein modification in plants: Evolution and function.

Authors:  Neil E Olszewski; Christopher M West; Slim O Sassi; Lynn M Hartweck
Journal:  Biochim Biophys Acta       Date:  2009-12-02

Review 10.  Chemical approaches to study O-GlcNAcylation.

Authors:  Partha S Banerjee; Gerald W Hart; Jin Won Cho
Journal:  Chem Soc Rev       Date:  2012-12-18       Impact factor: 54.564
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.