Literature DB >> 18533418

Investigation of soft-tissue stiffness alteration in denervated human tissue using an ultrasound indentation system.

Mohsen Makhsous1, Ganapriya Venkatasubramanian, Aditya Chawla, Yagna Pathak, Michael Priebe, William Z Rymer, Fang Lin.   

Abstract

BACKGROUND/
OBJECTIVE: Differences in soft-tissue stiffness may provide for a quantitative assessment and detection technique for pressure ulcers or deep-tissue injury. An ultrasound indentation system may provide a relatively convenient, simple, and noninvasive method for quantitative measurement of changes in soft-tissue stiffness in vivo.
METHODS: The Tissue Ultrasound Palpation System (TUPS) was used to quantitatively measure changes in soft-tissue stiffness at different anatomical locations within and between able-bodied persons and individuals with chronic spinal cord injury (SCI). The stiffness of soft tissue was measured at the ischial tuberosity, greater trochanter, posterior midthigh, and biceps brachii. Additionally, soft-tissue thickness and soft-tissue deformation were also measured.
RESULTS: Significant differences in soft-tissue stiffness were observed within the various anatomical locations tested, in both the able-bodied and SCI groups. Differences in soft-tissue stiffness were also observed between the 2 groups. Participants with SCI had significantly softer tissue in their buttock-thigh area.
CONCLUSIONS: TUPS is a clinically feasible technology that can reliably and effectively detect changes in soft-tissue stiffness. The study has provided a better understanding of the tissue mechanical response to external loading, specifically in the SCI population, suggesting the use of tissue stiffness as a parameter to detect and assess pressure-related soft-tissue injury.

Entities:  

Mesh:

Year:  2008        PMID: 18533418      PMCID: PMC2435021          DOI: 10.1080/10790268.2008.11753987

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  46 in total

1.  Assessment of neck tissue fibrosis using an ultrasound palpation system: a feasibility study.

Authors:  Y P Zheng; S F Leung; A F Mak
Journal:  Med Biol Eng Comput       Date:  2000-09       Impact factor: 2.602

2.  Passive transverse mechanical properties of skeletal muscle under in vivo compression.

Authors:  E M Bosboom; M K Hesselink; C W Oomens; C V Bouten; M R Drost; F P Baaijens
Journal:  J Biomech       Date:  2001-10       Impact factor: 2.712

3.  Microstructural and mechanical characterization of human tissue at and adjacent to pressure ulcers.

Authors:  L E Edsberg; R Cutway; S Anain; J R Natiella
Journal:  J Rehabil Res Dev       Date:  2000 Jul-Aug

4.  Moving toward consensus on deep tissue injury and pressure ulcer staging.

Authors:  Joyce M Black
Journal:  Adv Skin Wound Care       Date:  2005-10       Impact factor: 2.347

Review 5.  Pressure-related deep tissue injury under intact skin and the current pressure ulcer staging systems.

Authors:  Michael A Ankrom; Richard G Bennett; Stephen Sprigle; Diane Langemo; Joyce M Black; Dan R Berlowitz; Courtney H Lyder
Journal:  Adv Skin Wound Care       Date:  2005 Jan-Feb       Impact factor: 2.347

6.  Collagen fibril diameters increase and fibril densities decrease in skin subjected to repetitive compressive and shear stresses.

Authors:  J E Sanders; B S Goldstein
Journal:  J Biomech       Date:  2001-12       Impact factor: 2.712

7.  Biomechanical assessment of plantar foot tissue in diabetic patients using an ultrasound indentation system.

Authors:  Y P Zheng; Y K Choi; K Wong; S Chan; A F Mak
Journal:  Ultrasound Med Biol       Date:  2000-03       Impact factor: 2.998

Review 8.  Pressure ulcers. Analysis of guidelines for treatment and management.

Authors:  F A Cervo; A C Cruz; J A Posillico
Journal:  Geriatrics       Date:  2000-03

9.  Microstructural characteristics of human skin subjected to static versus cyclic pressures.

Authors:  L E Edsberg; J R Natiella; R E Baier; J Earle
Journal:  J Rehabil Res Dev       Date:  2001 Sep-Oct

10.  Intraoperatively acquired pressure ulcer prevalence: a national study.

Authors:  S A Aronovitch
Journal:  J Wound Ostomy Continence Nurs       Date:  1999-05       Impact factor: 1.741

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  5 in total

1.  The relationship between pressure offloading and ischial tissue health in individuals with spinal cord injury: An exploratory study.

Authors:  Sharon Gabison; Sunita Mathur; Ethne L Nussbaum; Milos R Popovic; Mary C Verrier
Journal:  J Spinal Cord Med       Date:  2019-10       Impact factor: 1.985

2.  In vivo soft tissue compressive properties of the human hand.

Authors:  Victoria Spartacus; Maedeh Shojaeizadeh; Vincent Raffault; James Shoults; Ken Van Wieren; Carolyn J Sparrey
Journal:  PLoS One       Date:  2021-12-13       Impact factor: 3.240

3.  Effect of loading history on material properties of human heel pad: an in-vivo pilot investigation during gait.

Authors:  Zhao-Lin Teng; Xiong-Gang Yang; Xiang Geng; Yan-Jie Gu; Ran Huang; Wen-Ming Chen; Chen Wang; Li Chen; Chao Zhang; Maimaitirexiati Helili; Jia-Zhang Huang; Xu Wang; Xin Ma
Journal:  BMC Musculoskelet Disord       Date:  2022-03-15       Impact factor: 2.362

4.  Buttock tissue response to loading in men with spinal cord injury.

Authors:  Sharon Eve Sonenblum; Stephen H Sprigle
Journal:  PLoS One       Date:  2018-02-07       Impact factor: 3.240

5.  Reference data on thickness and mechanics of tissue layers and anthropometry of musculoskeletal extremities.

Authors:  Erica E Neumann; Tammy M Owings; Tyler Schimmoeller; Tara F Nagle; Robb W Colbrunn; Benjamin Landis; J Eric Jelovsek; Mike Wong; Joy P Ku; Ahmet Erdemir
Journal:  Sci Data       Date:  2018-09-25       Impact factor: 6.444

  5 in total

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