| Literature DB >> 18524594 |
Shiori Oshimi1, Yuichiro Tomizawa, Yusuke Hirasawa, Toshio Honda, Wiwied Ekasari, Aty Widyawaruyanti, Marcellino Rudyanto, Gunawan Indrayanto, Noor Cholies Zaini, Hiroshi Morita.
Abstract
A new bischromone, chrobisiamone A (1) with an antiplasmodial activity has been isolated from the leaves of Cassia siamea and the structure was elucidated by 2D NMR analysis. Cyclization of 5-acetonyl-7-hydroxy-2-methylchromone (2) in the presence of ammonium acetate resulted in generation of cassiarin A (3) with an unprecedented tricyclic skeleton, supporting a biogenetic pathway proposed for 3.Entities:
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Year: 2008 PMID： 18524594 DOI： 10.1016/j.bmcl.2008.05.041
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823