Literature DB >> 18524424

"Self-activating" chemical nuclease: ferrocenyl cyclen Cu(II) complexes act as efficient DNA cleavage reagents in the absence of reductant.

Kun Li1, Li-Hong Zhou, Ji Zhang, Shan-Yong Chen, Zhong-Wei Zhang, Jing-Jing Zhang, Hong-Hui Lin, Xiao-Qi Yu.   

Abstract

The interactions of cyclen Cu(II) complexes functionalized by ferrocenyl group with plasmid DNA indicated that these complexes have high cleavage efficiency via an oxidative mechanism in the absence of any reductant or oxidant.

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Year:  2008        PMID： 18524424     DOI： 10.1016/j.ejmech.2008.03.029

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  3 in total

1.  Coordination Chemistry of Polyaromatic Thiosemicarbazones 2: Synthesis and Biological Activity of Zinc, Cobalt, and Copper Complexes of 1-(Naphthalene-2-yl)ethanone Thiosemicarbazone.

Authors:  Marc-Andre Leblanc; Antonio Gonzalez-Sarrías; Floyd A Beckford; P Canisius Mbarushimana; Navindra P Seeram
Journal:  Int J Inorg Chem       Date:  2011-01-01

2.  Nuclease activity via self-activation and anticancer activity of a mononuclear copper(II) complex: novel role of the tertiary butyl group in the ligand frame.

Authors:  Kaushik Ghosh; Pramod Kumar; Varun Mohan; Udai P Singh; Sahba Kasiri; Subhrangsu S Mandal
Journal:  Inorg Chem       Date:  2012-02-28       Impact factor: 5.165

3.  Investigating Alkylated Prodigiosenes and Their Cu(II)-Dependent Biological Activity: Interactions with DNA, Antimicrobial and Photoinduced Anticancer Activity.

Authors:  Sebastian Doniz Kettenmann; Matthew White; Julien Colard-Thomas; Matilda Kraft; Andrea T Feßler; Karin Danz; Gerhard Wieland; Sylvia Wagner; Stefan Schwarz; Arno Wiehe; Nora Kulak
Journal:  ChemMedChem       Date:  2021-12-22       Impact factor: 3.540
  3 in total

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