Literature DB >> 18521392

A radiotherapy technique to improve dose homogeneity around bone prostheses.

M V Williams1, N G Burnet, E Sherwin, R Kestelman, A R Geater, S J Thomas, C B Wilson.   

Abstract

Purpose. Following limb conserving surgery for bone or soft tissue sarcoma, patients may require post-operative radiotherapy to minimise the risk of local recurrence. In such circumstances the metal prosthesis reduces the dose in its shadow by approximately 10% when using opposed fields. We describe a technique to boost the underdosed area to overcome this problem.Patients or subjects. Seven sequential patients presenting between 1995 and 2001 had their treatment individualised because they had metal prosthesis in the treatment volume.Methods. To improve the target dose homogeneity we used a custom-made keyhole cutout to boost the area in the shadow of the prosthesis. The degree of attenuation caused by the metal prosthesis was estimated and a boost dose calculated. Exit thermoluminescent dosimetry (TLD) was used to confirm the estimates made.Results and discussion. Variation between patients was seen, demonstrating the need for exit TLD to individualise the treatment plan. The use of a boost field provides a method to overcome under-dosage in the shadow of a metal prosthesis. It improves dose homogeneity throughout the target volume and ensures adequate dose intensity around the prosthesis, the site most at risk of local recurrence.

Entities:  

Year:  2004        PMID: 18521392      PMCID: PMC2395598          DOI: 10.1080/13577140410001679248

Source DB:  PubMed          Journal:  Sarcoma        ISSN: 1357-714X


  17 in total

1.  Dosimetric considerations for patients with HIP prostheses undergoing pelvic irradiation. Report of the AAPM Radiation Therapy Committee Task Group 63.

Authors:  Chester Reft; Rodica Alecu; Indra J Das; Bruce J Gerbi; Paul Keall; Eugene Lief; Ben J Mijnheer; Nikos Papanikolaou; Claudio Sibata; Jake Van Dyk
Journal:  Med Phys       Date:  2003-06       Impact factor: 4.071

2.  Osteogenic sarcoma; a study based on 133 patients.

Authors:  S CADE
Journal:  J R Coll Surg Edinb       Date:  1955-12

3.  Planning of radiotherapy for patients with hip prosthesis.

Authors:  M Erlanson; L Franzén; R Henriksson; B Littbrand; P O Löfroth
Journal:  Int J Radiat Oncol Biol Phys       Date:  1991-05       Impact factor: 7.038

4.  Osteosarcoma. An assessment of management with particular reference to primary irradiation and selective delayed amputation.

Authors:  R D Jenkin; W E Allt; P J Fitzpatrick
Journal:  Cancer       Date:  1972-08       Impact factor: 6.860

5.  Hip prostheses during pelvic irradiation: effects and corrections.

Authors:  M B Hazuka; G S Ibbott; J J Kinzie
Journal:  Int J Radiat Oncol Biol Phys       Date:  1988-06       Impact factor: 7.038

6.  Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the istituto ortopedico rizzoli according to the istituto ortopedico rizzoli/osteosarcoma-2 protocol: an updated report.

Authors:  G Bacci; S Ferrari; F Bertoni; P Ruggieri; P Picci; A Longhi; R Casadei; N Fabbri; C Forni; M Versari; M Campanacci
Journal:  J Clin Oncol       Date:  2000-12-15       Impact factor: 44.544

7.  Treatment of nonmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group.

Authors:  A J Provisor; L J Ettinger; J B Nachman; M D Krailo; J T Makley; E J Yunis; A G Huvos; D L Betcher; E S Baum; C T Kisker; J S Miser
Journal:  J Clin Oncol       Date:  1997-01       Impact factor: 44.544

8.  Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate (high versus moderate doses) and intraarterial cisplatin.

Authors:  G Bacci; P Picci; P Ruggieri; M Mercuri; M Avella; R Capanna; A Brach Del Prever; A Mancini; F Gherlinzoni; G Padovani
Journal:  Cancer       Date:  1990-06-01       Impact factor: 6.860

9.  The effect of local control on metastatic dissemination in carcinoma of the prostate: long-term results in patients treated with 125I implantation.

Authors:  Z Fuks; S A Leibel; K E Wallner; C B Begg; W R Fair; L L Anderson; B S Hilaris; W F Whitmore
Journal:  Int J Radiat Oncol Biol Phys       Date:  1991-08       Impact factor: 7.038

10.  Osteosarcoma of the pelvis: experience of the Cooperative Osteosarcoma Study Group.

Authors:  Toshifumi Ozaki; Silke Flege; Matthias Kevric; Norbert Lindner; Rainer Maas; Günter Delling; Rudolf Schwarz; Arthur R von Hochstetter; Mechthild Salzer-Kuntschik; Wolfgang E Berdel; Heribert Jürgens; G Ulrich Exner; Peter Reichardt; Regine Mayer-Steinacker; Volker Ewerbeck; Rainer Kotz; Winfried Winkelmann; Stefan S Bielack
Journal:  J Clin Oncol       Date:  2003-01-15       Impact factor: 44.544

View more
  3 in total

1.  An opposed matched field IMRT technique for prostate cancer patients with bilateral prosthetic hips.

Authors:  Shahin Fattahi; Orest Z Ostapiak
Journal:  J Appl Clin Med Phys       Date:  2012-01-05       Impact factor: 2.102

2.  Evaluation of dose calculation accuracy of treatment planning systems at hip prosthesis interfaces.

Authors:  David Paulu; Parham Alaei
Journal:  J Appl Clin Med Phys       Date:  2017-03-20       Impact factor: 2.102

3.  Investigating the Impact of Knee Prosthesis in Patients' Body on Radiation Dose Distribution: A Monte Carlo Approach.

Authors:  Bayatiani M R; Seif F; Hamidi S; Bagheri S
Journal:  J Biomed Phys Eng       Date:  2019-06-01
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.