| Literature DB >> 18519714 |
Ines Schneider1, Emma Keuleyan, Rudolf Rasshofer, Rumyana Markovska, Anne Marie Queenan, Adolf Bauernfeind.
Abstract
Two Pseudomonas aeruginosa urine isolates from Bulgaria and Germany produced two new VIM-2 variants. VIM-15 had one amino acid substitution (Tyr218Phe) which caused a significant increase in hydrolytic efficiency. The substitution Ser54Leu, characterizing VIM-16, showed no influence on enzyme activity. Both genes were part of class I integrons located in the chromosome.Entities:
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Year: 2008 PMID: 18519714 PMCID: PMC2493107 DOI: 10.1128/AAC.00175-08
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191