| Literature DB >> 1851804 |
M Martín1, A Gibello, J Fernández, E Ferrer, A Garrido-Pertierra.
Abstract
Klebsiella pneumoniae catabolizes both 4-hydroxyphenylacetic acid and 3-hydroxyphenylacetic acid via meta-cleavage of 3,4-dihydroxyphenylacetic acid, ultimately yielding pyruvate and succinate. The organism can synthesize two hydroxylases catalysing 3,4-dihydroxyphenylacetic acid formation, which differ in substrate specificity, cofactor requirement, kinetics and regulation. Five enzymes sequentially involved in the catabolism of 3,4-dihydroxyphenylacetic acid are encoded on a 7 kbp fragment of the K. pneumoniae chromosome that has been isolated in a recombinant plasmid.Entities:
Mesh：
Substances：
Year: 1991 PMID： 1851804 DOI： 10.1099/00221287-137-3-621
Source DB: PubMed Journal: J Gen Microbiol ISSN： 0022-1287