Literature DB >> 18515823

SNP analysis to results (SNPator): a web-based environment oriented to statistical genomics analyses upon SNP data.

Carlos Morcillo-Suarez1, Josep Alegre, Ricardo Sangros, Elodie Gazave, Rafael de Cid, Roger Milne, Jorge Amigo, Anna Ferrer-Admetlla, Andrés Moreno-Estrada, Michelle Gardner, Ferran Casals, Anna Pérez-Lezaun, David Comas, Elena Bosch, Francesc Calafell, Jaume Bertranpetit, Arcadi Navarro.   

Abstract

UNLABELLED: Single nucleotide polymorphisms (SNPs) are the most widely used marker in studies to assess associations between genetic variants and complex traits or diseases. They are also becoming increasingly important in the study of the evolution and history of humans and other species. The analysis and processing of SNPs obtained thanks to high-throughput technologies imply the time consuming and costly use of different, complex and usually format-incompatible software. SNPator is a user-friendly web-based SNP data analysis suite that integrates, among many other algorithms, the most common steps of a SNP association study. It frees the user from the need to have large computer facilities and an in depth knowledge of genetic software installation and management. Genotype data is directly read from the output files of the usual genotyping platforms. Phenotypic data on the samples can also be easily uploaded. Many different quality control and analysis procedures can be performed either by using built-in SNPator algorithms or by calling standard genetic software. AVAILABILITY: Access is granted from the SNPator webpage http://www.snpator.org.

Entities:  

Mesh:

Year:  2008        PMID: 18515823     DOI: 10.1093/bioinformatics/btn241

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  28 in total

1.  Isolated populations as treasure troves in genetic epidemiology: the case of the Basques.

Authors:  Paolo Garagnani; Hafid Laayouni; Anna González-Neira; Martin Sikora; Donata Luiselli; Jaume Bertranpetit; Francesc Calafell
Journal:  Eur J Hum Genet       Date:  2009-05-06       Impact factor: 4.246

2.  Intraethnic variation in steroid-5-alpha-reductase polymorphismsin prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment.

Authors:  Luis Alberto Henríquez-Hernández; Almudena Valenciano; Palmira Foro-Arnalot; María Jesús Álvarez-Cubero; José Manuel Cozar; José Francisco Suárez-Novo; Manel Castells-Esteve; Pablo Fernández-Gonzalo; Belén De-Paula-Carranza; Montse Ferrer; Ferrán Guedea; Gemma Sancho-Pardo; Jordi Craven-Bartle; María José Ortiz-Gordillo; Patricia Cabrera-Roldán; Estefanía Herrera-Ramos; Carlos Rodríguez-Gallego; Pedro C Lara
Journal:  J Genet       Date:  2015-06       Impact factor: 1.166

3.  Association between single-nucleotide polymorphisms in DNA double-strand break repair genes and prostate cancer aggressiveness in the Spanish population.

Authors:  L A Henríquez-Hernández; A Valenciano; P Foro-Arnalot; M J Álvarez-Cubero; J M Cozar; J F Suárez-Novo; M Castells-Esteve; P Fernández-Gonzalo; B De-Paula-Carranza; M Ferrer; F Guedea; G Sancho-Pardo; J Craven-Bartle; M J Ortiz-Gordillo; P Cabrera-Roldán; J I Rodríguez-Melcón; E Herrera-Ramos; C Rodríguez-Gallego; P C Lara
Journal:  Prostate Cancer Prostatic Dis       Date:  2016-01-12       Impact factor: 5.554

4.  A Trans-acting Factor May Modify Age at Onset in Familial Amyloid Polyneuropathy ATTRV30M in Portugal.

Authors:  Miguel Alves-Ferreira; Teresa Coelho; Diana Santos; Jorge Sequeiros; Isabel Alonso; Alda Sousa; Carolina Lemos
Journal:  Mol Neurobiol       Date:  2017-05-19       Impact factor: 5.590

5.  Copy number variation analysis in the great apes reveals species-specific patterns of structural variation.

Authors:  Elodie Gazave; Fleur Darré; Carlos Morcillo-Suarez; Natalia Petit-Marty; Angel Carreño; Urko M Marigorta; Oliver A Ryder; Antoine Blancher; Mariano Rocchi; Elena Bosch; Carl Baker; Tomàs Marquès-Bonet; Evan E Eichler; Arcadi Navarro
Journal:  Genome Res       Date:  2011-08-08       Impact factor: 9.043

6.  Genetic association study of age-related macular degeneration in the Spanish population.

Authors:  María Brión; Manuel Sanchez-Salorio; Marta Cortón; Maria de la Fuente; Belen Pazos; Mohammad Othman; Anand Swaroop; Goncalo Abecasis; Beatriz Sobrino; Angel Carracedo
Journal:  Acta Ophthalmol       Date:  2010-11-25       Impact factor: 3.761

7.  Variants in RBP4 and AR genes modulate age at onset in familial amyloid polyneuropathy (FAP ATTRV30M).

Authors:  Diana Santos; Teresa Coelho; Miguel Alves-Ferreira; Jorge Sequeiros; Denisa Mendonça; Isabel Alonso; Carolina Lemos; Alda Sousa
Journal:  Eur J Hum Genet       Date:  2015-08-19       Impact factor: 4.246

8.  How immunogenetically different are domestic pigs from wild boars: a perspective from single-nucleotide polymorphisms of 19 immunity-related candidate genes.

Authors:  Shanyuan Chen; Rui Gomes; Vânia Costa; Pedro Santos; Rui Charneca; Ya-ping Zhang; Xue-hong Liu; Shao-qing Wang; Pedro Bento; Jose-Luis Nunes; József Buzgó; Gyula Varga; István Anton; Attila Zsolnai; Albano Beja-Pereira
Journal:  Immunogenetics       Date:  2013-07-12       Impact factor: 2.846

9.  Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD.

Authors:  Elena Bosch; Hafid Laayouni; Carlos Morcillo-Suarez; Ferran Casals; Andrés Moreno-Estrada; Anna Ferrer-Admetlla; Michelle Gardner; Araceli Rosa; Arcadi Navarro; David Comas; Jan Graffelman; Francesc Calafell; Jaume Bertranpetit
Journal:  BMC Genomics       Date:  2009-07-28       Impact factor: 3.969

10.  A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study.

Authors:  Miguel Alves-Ferreira; Marlene Quintas; Jorge Sequeiros; Alda Sousa; José Pereira-Monteiro; Isabel Alonso; João Luís Neto; Carolina Lemos
Journal:  J Headache Pain       Date:  2021-06-14       Impact factor: 7.277

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