Literature DB >> 18511173

Neurobiology of cognitive aging: insights from imaging genetics.

Venkata S Mattay1, Terry E Goldberg, Fabio Sambataro, Daniel R Weinberger.   

Abstract

Over the last several years, neuroscientists have been increasingly using neuroimaging techniques to unravel the neurobiology underlying cognitive aging, and in more recent years to explore the role of genes on the variability of the aging process. One of the primary goals of this research is to identify proteins involved in cognitive aging with the hope that this would facilitate the development of novel treatments to combat cognitive impairment. Further, it is likely with early identification of susceptible individuals, early intervention through life-style changes and other methods could increase an individual's resilience to the effects of aging.

Entities:  

Mesh：

Year:  2008        PMID： 18511173      PMCID： PMC3127547          DOI： 10.1016/j.biopsycho.2008.03.015

Source DB:  PubMed          Journal:  Biol Psychol        ISSN： 0301-0511            Impact factor:   3.251


  109 in total

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Review 3.  Brain imaging as an approach to phenotype characterization for genetic studies of schizophrenia.

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10.  Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: evidence from diffusion tensor imaging.

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  26 in total

1.  [Genetic aspects of cognitive abilities across the life span].

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Journal:  Biol Psychiatry       Date:  2011-02-11       Impact factor: 13.382

3.  SORL1 rs1699102 polymorphism modulates age-related cognitive decline and gray matter volume reduction in non-demented individuals.

Authors:  He Li; Chenlong Lv; Caishui Yang; Dongfeng Wei; Kewei Chen; Shaowu Li; Zhanjun Zhang
Journal:  Eur J Neurol       Date:  2016-10-25       Impact factor: 6.089

Review 4.  The continuing value of twin studies in the omics era.

Authors:  Jenny van Dongen; P Eline Slagboom; Harmen H M Draisma; Nicholas G Martin; Dorret I Boomsma
Journal:  Nat Rev Genet       Date:  2012-07-31       Impact factor: 53.242

Review 5.  Between destiny and disease: genetics and molecular pathways of human central nervous system aging.

Authors:  Christin Glorioso; Etienne Sibille
Journal:  Prog Neurobiol       Date:  2010-12-02       Impact factor: 11.685

6.  BDNF Val66Met polymorphism influences age differences in microstructure of the Corpus Callosum.

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7.  WWC1 genotype modulates age-related decline in episodic memory function across the adult life span.

Authors:  John Muse; Matthew Emery; Fabio Sambataro; Herve Lemaitre; Hao-Yang Tan; Qiang Chen; Bhaskar S Kolachana; Saumitra Das; Joseph H Callicott; Daniel R Weinberger; Venkata S Mattay
Journal:  Biol Psychiatry       Date:  2013-10-18       Impact factor: 13.382

8.  Synergistic effects of the MTHFR C677T polymorphism and hypertension on spatial navigation.

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9.  Impact of APOE on the healthy aging brain: a voxel-based MRI and DTI study.

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Journal:  J Alzheimers Dis       Date:  2009       Impact factor: 4.472

10.  Frontoparietal cortical thickness mediates the effect of COMT Val158Met polymorphism on age-associated executive function.

Authors:  Giuseppe G Miranda; Karen M Rodrigue; Kristen M Kennedy
Journal:  Neurobiol Aging       Date:  2018-09-21       Impact factor: 4.673
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