Literature DB >> 18503457

Horse Chestnut - Aesculus Hippocastanum: Potential Applications in Cosmetic Skin-care Products.

J A Wilkinson1, A M Brown.   

Abstract

In addition to the well reported beneficial effects of horse chestnut (Aesculus hippocastanum) extracts on venous insufficiency and associated conditions, such preparations also have many potential positive pharmacological effects on the skin. Extracts from this species, and in particular, those based on horse chestnut seeds, contain saponins, known collectively as 'aescin', which have a gentle soapy feel, and are potent anti-inflammatory compounds. Saponins, such as escin, also reduce capillary fragility, and therefore help to prevent leakage of fluids into surrounding tissues, which can cause swelling. An extract of horse chestnut has recently been shown to have one of the highest 'active-oxygen' scavenging abilities of 65 different plant extracts tested. Such extracts are more powerful anti-oxidants than vitamin E, and also exhibit potent cell-protective effects, which are linked to the well-known anti-ageing properties of anti-oxidants. The extract is also rich in a number of flavonoids, such as derivatives of quercetin and kaempferol. Flavonoids also have protective effects on blood vessels, and are well-known, powerful anti-oxidants.

Entities:  

Year:  1999        PMID: 18503457     DOI: 10.1046/j.1467-2494.1999.234192.x

Source DB:  PubMed          Journal:  Int J Cosmet Sci        ISSN: 0142-5463            Impact factor:   2.970


  9 in total

1.  Toxicity and Anti-feeding effect of Aesculushippocastanum, Thymus daenensis, Artemisia abrotanum, and Chrozophora tinctoria on Sitophillus oryzae.

Authors:  Reza Sadeghnezhad; Sepideh Abbaszadeh; Maryam Taghdir; Mojtaba Sepandi; Mahmoud Fazeli-Dinan; Mohammad Ali Zazouli
Journal:  J Environ Health Sci Eng       Date:  2022-01-29

2.  Beta-escin has potent anti-allergic efficacy and reduces allergic airway inflammation.

Authors:  Ines Lindner; Christiane Meier; Angelika Url; Hermann Unger; Andreas Grassauer; Eva Prieschl-Grassauer; Petra Doerfler
Journal:  BMC Immunol       Date:  2010-05-21       Impact factor: 3.615

3.  In-vitro Antioxidant Activities of the Ethanolic Extracts of Some Contained-Allantoin Plants.

Authors:  Zeliha Selamoglu; Cihan Dusgun; Hasan Akgul; Mehmet Fuat Gulhan
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

4.  Aescin-Cholesterol Complexes in DMPC Model Membranes: A DSC and Temperature-Dependent Scattering Study.

Authors:  Ramsia Sreij; Carina Dargel; Ralf Schweins; Sylvain Prévost; Rajeev Dattani; Thomas Hellweg
Journal:  Sci Rep       Date:  2019-04-03       Impact factor: 4.379

5.  Aesculus hippocastanum L. as a Stabilizer in Hemp Seed Oil Nanoemulsions for Potential Biomedical and Food Applications.

Authors:  Maciej Jarzębski; Wojciech Smułek; Przemysław Siejak; Ryszard Rezler; Jarosław Pawlicz; Tomasz Trzeciak; Małgorzata Jarzębska; Oliwia Majchrzak; Ewa Kaczorek; Pardis Kazemian; Marta Ponieważ-Pawlicz; Farahnaz Fathordoobady
Journal:  Int J Mol Sci       Date:  2021-01-17       Impact factor: 5.923

6.  Poisoning due to consumption of horse chestnut seed.

Authors:  Hwa Yeon Yi; Jang Young Lee
Journal:  Clin Exp Emerg Med       Date:  2021-12-31

Review 7.  Tissue Culture Response of Ornamental and Medicinal Aesculus Species-A Review.

Authors:  Snežana Zdravković-Korać; Jelena Milojević; Maja Belić; Dušica Ćalić
Journal:  Plants (Basel)       Date:  2022-01-20

8.  Hypoglycemic and Anti-Inflammatory Effects of Triterpene Glycoside Fractions from Aeculus hippocastanum Seeds.

Authors:  Avez Sharipov; Khurshid Tursunov; Sunnatullo Fazliev; Bahtigul Azimova; Jamoliddin Razzokov
Journal:  Molecules       Date:  2021-06-22       Impact factor: 4.411

Review 9.  The Biosurfactant β-Aescin: A Review on the Physico-Chemical Properties and Its Interaction with Lipid Model Membranes and Langmuir Monolayers.

Authors:  Ramsia Geisler; Carina Dargel; Thomas Hellweg
Journal:  Molecules       Date:  2019-12-27       Impact factor: 4.411

  9 in total

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