Literature DB >> 18500376

Drugs in sport.

J C McGrath1, D A Cowan.   

Abstract

This themed issue of the British Journal of Pharmacology has been compiled and edited by Ian McGrath, Regius Professor of Physiology at University of Glasgow and David Cowan, Director of the Drug Control Centre at King's College London. It contains 11 articles covering the mechanisms of action of the major groups of drugs used illicitly in sport. The articles, written by experts in how drugs work, set out where drugs can or cannot affect sporting performance, how this relates to their legitimate medicinal use, their other detrimental effects and how they can be detected. Publication coincides with Olympic year, when sport is highlighted in the public mind and much speculation is made concerning the use of drugs. The articles provide a framework of expert, accurate knowledge to inform and facilitate these debates and to help to overcome the ill-informed and dangerous anecdotal information by which sports men and women are persuaded to misuse drugs in the mistaken belief that this will improve their performance without present or future ill effects. A unique article is included by the Spedding brothers, Mike with a long career in drug discovery and Charlie, the 1984 Los Angeles Olympic Marathon Bronze Medallist and still the English National Marathon record holder. From their unique experience, they describe the insidious and unfair way that drug-assisted performance undermines the ethos of sport and endangers the vital place of sport in maintaining the health of the population.

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Mesh:

Year:  2008        PMID: 18500376      PMCID: PMC2439512          DOI: 10.1038/bjp.2008.171

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  11 in total

Review 1.  The rush to adrenaline: drugs in sport acting on the beta-adrenergic system.

Authors:  E Davis; R Loiacono; R J Summers
Journal:  Br J Pharmacol       Date:  2008-06       Impact factor: 8.739

Review 2.  Gene doping: the hype and the reality.

Authors:  D J Wells
Journal:  Br J Pharmacol       Date:  2008-04-21       Impact factor: 8.739

Review 3.  Pharmacology of stimulants prohibited by the World Anti-Doping Agency (WADA).

Authors:  J R Docherty
Journal:  Br J Pharmacol       Date:  2008-06       Impact factor: 8.739

Review 4.  Drugs in sport: a scientist-athlete's perspective: from ambition to neurochemistry.

Authors:  M Spedding; C Spedding
Journal:  Br J Pharmacol       Date:  2008-06       Impact factor: 8.739

Review 5.  Erythropoiesis-stimulating agents and other methods to enhance oxygen transport.

Authors:  S Elliott
Journal:  Br J Pharmacol       Date:  2008-03-24       Impact factor: 8.739

Review 6.  Gonadotropins in doping: pharmacological basis and detection of illicit use.

Authors:  U-H Stenman; K Hotakainen; H Alfthan
Journal:  Br J Pharmacol       Date:  2008-04-14       Impact factor: 8.739

Review 7.  Cellular and molecular mechanisms responsible for the action of testosterone on human skeletal muscle. A basis for illegal performance enhancement.

Authors:  F Kadi
Journal:  Br J Pharmacol       Date:  2008-04-14       Impact factor: 8.739

Review 8.  Regulation of muscle mass by growth hormone and IGF-I.

Authors:  C P Velloso
Journal:  Br J Pharmacol       Date:  2008-06       Impact factor: 8.739

Review 9.  Indirect androgen doping by oestrogen blockade in sports.

Authors:  D J Handelsman
Journal:  Br J Pharmacol       Date:  2008-04-21       Impact factor: 8.739

Review 10.  Growth hormone, IGF-I and insulin and their abuse in sport.

Authors:  R I G Holt; P H Sönksen
Journal:  Br J Pharmacol       Date:  2008-03-31       Impact factor: 8.739

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  2 in total

Review 1.  The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: pharmacology, toxicology and analysis.

Authors:  Amy B Cadwallader; Xavier de la Torre; Alessandra Tieri; Francesco Botrè
Journal:  Br J Pharmacol       Date:  2010-09       Impact factor: 8.739

2.  Continuity and change.

Authors:  H P Rang; J C McGrath
Journal:  Br J Pharmacol       Date:  2009-01       Impact factor: 8.739

  2 in total

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