Literature DB >> 18482563

Type 1 interferons cool the inflamed brain.

Robert C Axtell1, Lawrence Steinman.   

Abstract

Although interferon-beta is the most popular treatment for multiple sclerosis, its mechanism of action remains enigmatic. In this issue of Immunity, Prinz et al. (2008) elucidate an intriguing portrait of the pleiotropic effects of type 1 interferons in taming brain inflammation.

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Year:  2008        PMID： 18482563     DOI： 10.1016/j.immuni.2008.04.006

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  18 in total

1.  Quantitative differences in the immunomodulatory effects of Rebif and Avonex in IFN-β 1a treated multiple sclerosis patients.

Authors:  George P Christophi; Jennifer A Christophi; Ross C Gruber; Cornelia Mihai; Luis J Mejico; Paul T Massa; Burk Jubelt
Journal:  J Neurol Sci       Date:  2011-06-11       Impact factor: 3.181

Review 2.  Nuanced roles of cytokines in three major human brain disorders.

Authors:  Lawrence Steinman
Journal:  J Clin Invest       Date:  2008-11       Impact factor: 14.808

Review 3.  Regulation of T-helper-cell lineage development by osteopontin: the inside story.

Authors:  Harvey Cantor; Mari L Shinohara
Journal:  Nat Rev Immunol       Date:  2009-02       Impact factor: 53.106

4.  Interferon-β Inhibits Neurotrophin 3 Signalling and Pro-Survival Activity by Upregulating the Expression of Truncated TrkC-T1 Receptor.

Authors:  Simona Dedoni; Maria C Olianas; Angela Ingianni; Pierluigi Onali
Journal:  Mol Neurobiol       Date:  2016-02-18       Impact factor: 5.590

5.  Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.

Authors:  George P Christophi; Michael Panos; Chad A Hudson; Chriso Tsikkou; Cornelia Mihai; Luis J Mejico; Burk Jubelt; Paul T Massa
Journal:  Clin Immunol       Date:  2009-06-25       Impact factor: 3.969

Review 6.  Signaling by cGAS-STING in Neurodegeneration, Neuroinflammation, and Aging.

Authors:  Bindu D Paul; Solomon H Snyder; Vilhelm A Bohr
Journal:  Trends Neurosci       Date:  2020-11-10       Impact factor: 13.837

7.  Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function.

Authors:  Kuti Baruch; Aleksandra Deczkowska; Eyal David; Joseph M Castellano; Omer Miller; Alexander Kertser; Tamara Berkutzki; Zohar Barnett-Itzhaki; Dana Bezalel; Tony Wyss-Coray; Ido Amit; Michal Schwartz
Journal:  Science       Date:  2014-08-21       Impact factor: 47.728

8.  Overview of the biology of type I interferons.

Authors:  George D Kalliolias; Lionel B Ivashkiv
Journal:  Arthritis Res Ther       Date:  2010-04-14       Impact factor: 5.156

9.  Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis.

Authors:  Sienmi Du; Francisco Sandoval; Pauline Trinh; Rhonda R Voskuhl
Journal:  J Neuroimmunol       Date:  2009-12-14       Impact factor: 3.478

10.  Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.

Authors:  Fangfang Lu; Ronglin Wang; Li Xia; Tiejian Nie; Fei Gao; Shaosong Yang; Lu Huang; Kaifeng Shao; Jiankang Liu; Qian Yang
Journal:  J Inflamm Res       Date:  2021-06-29
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