Literature DB >> 18476703

Synthesis of spiro-bisperoxyketals.

Prasanta Ghorai1, Patrick H Dussault, Chunhua Hu.   

Abstract

Syntheses of spirocyclic bis-1,2-dioxolanes, bis-1,2-dioxanes, and bis-1,2-dioxepanes are achieved through intramolecular ketalizations of hydroperoxy ketones or intramolecular alkylations of gem-dihydroperoxides. The spiroperoxides have excellent thermal and chemical stability, and several display promising activity against P. falciparum.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18476703     DOI： 10.1021/ol800657m

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  16 in total

1.  Cu(II)-catalyzed aerobic hydroperoxidation of Meldrum's acid derivatives and application in intramolecular oxidation: a conceptual blueprint for O2/H2 dihydroxylation.

Authors:  Scott W Krabbe; Dung T Do; Jeffrey S Johnson
Journal:  Org Lett       Date:  2012-11-19       Impact factor: 6.005

2.  Endoperoxide synthesis by photocatalytic aerobic [2 + 2 + 2] cycloadditions.

Authors:  Jonathan D Parrish; Michael A Ischay; Zhan Lu; Song Guo; Noël R Peters; Tehshik P Yoon
Journal:  Org Lett       Date:  2012-02-28       Impact factor: 6.005

3.  3-Alkoxy-1,2-Dioxolanes: Synthesis and Evaluation as Potential Antimalarial Agents.

Authors:  Charles E Schiaffo; Matthias Rottman; Sergio Wittlin; Patrick H Dussault
Journal:  ACS Med Chem Lett       Date:  2011-04-14       Impact factor: 4.345

Review 4.  Rearrangements of organic peroxides and related processes.

Authors:  Ivan A Yaremenko; Vera A Vil'; Dmitry V Demchuk; Alexander O Terent'ev
Journal:  Beilstein J Org Chem       Date:  2016-08-03       Impact factor: 2.883

5.  Asymmetric Synthesis of 1,2-dioxanes: Approaches to the Peroxyplakoric Acids.

Authors:  Chunping Xu; Chris Schwartz; Joseph Raible; Patrick H Dussault
Journal:  Tetrahedron       Date:  2009-11-21       Impact factor: 2.457

6.  Mn-, Fe-, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins.

Authors:  Steven W M Crossley; Carla Obradors; Ruben M Martinez; Ryan A Shenvi
Journal:  Chem Rev       Date:  2016-07-27       Impact factor: 60.622

7.  Perylenequinone natural products: total syntheses of the diastereomers (+)-phleichrome and (+)-calphostin D by assembly of centrochiral and axial chiral fragments.

Authors:  Barbara J Morgan; Carol A Mulrooney; Erin M O'Brien; Marisa C Kozlowski
Journal:  J Org Chem       Date:  2010-01-01       Impact factor: 4.354

8.  Design, synthesis, and investigation of protein kinase C inhibitors: total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones.

Authors:  Barbara J Morgan; Sangeeta Dey; Steven W Johnson; Marisa C Kozlowski
Journal:  J Am Chem Soc       Date:  2009-07-08       Impact factor: 15.419

9.  Synthesis of alkyl hydroperoxides via alkylation of gem-dihydroperoxides.

Authors:  ShivaKumar Kyasa; Benjamin W Puffer; Patrick H Dussault
Journal:  J Org Chem       Date:  2013-03-18       Impact factor: 4.354

10.  Palladium(II)-catalyzed cyclization of unsaturated hydroperoxides for the synthesis of 1,2-dioxanes.

Authors:  Jason R Harris; Shelli R Waetzig; K A Woerpel
Journal:  Org Lett       Date:  2009-08-06       Impact factor: 6.005
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.