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Literature DB >> 18475696

Serum levels of total IgE and soluble CD23 in bronchial asthma.

G D Lorenzo¹, P Mansueto, M Melluso, G Morici, D Cigna, G Candore, C Caruso.

Abstract

The aim of the present study was to compare, during the pollen season, serum levels of total IgE and soluble CD23 (sCD23) from patients with allergic bronchial asthma, with those from healthy subjects. Significantly higher levels of total IgE and sCD23 were found in patients with asthma compared to the control group. Both in normal controls and in asthmatic patients, a significant correlation was shown between the levels of these two molecules. In asthmatic patients, significant correlations were found for both total IgE and sCD23, with lung function measured as bronchial responsiveness to inhaled methacholine. These results suggest that in asthmatic patients, in addition to the study of total serum IgE levels, the assessment of sCD23 serum levels may be helpful in the evaluation of disease activity.

Entities: Chemical Disease Gene Species

Year: 1996 PMID： 18475696 PMCID： PMC2365763 DOI： 10.1155/S0962935196000075

Source DB: PubMed Journal: Mediators Inflamm ISSN： 0962-9351 Impact factor: 4.711

14 in total

1. The relationship between atopy and non-specific bronchial responsiveness.

Authors: D N Grainger; S C Stenton; A J Avery; M Duddridge; E H Walters; D J Hendrick
Journal: Clin Exp Allergy Date: 1990-03 Impact factor: 5.018

2. Prediction of the development of atopic symptoms in early childhood by cord IgE-binding factors (soluble Fc epsilon R2).

Authors: K M Kim; Y Inoue; Y Uenoyama; K Mutoh; J Yodoi; M Kaneshima; M Mayumi; H Mikawa
Journal: Immunol Lett Date: 1990 Mar-Apr Impact factor: 3.685

3. Soluble CD23 levels are inversely associated with atopy and parasite-specific IgE levels but not with polyclonal IgE levels in people exposed to helminth infection.

Authors: Nadine Rujeni; Norman Nausch; Nicholas Midzi; Reginald Gwisai; Takafira Mduluza; David W Taylor; Francisca Mutapi
Journal: Int Arch Allergy Immunol Date: 2013-05-14 Impact factor: 2.749

3 in total

Serum levels of total IgE and soluble CD23 in bronchial asthma.

1. The relationship between atopy and non-specific bronchial responsiveness.

2. Prediction of the development of atopic symptoms in early childhood by cord IgE-binding factors (soluble Fc epsilon R2).

3. Serum levels of IgE-binding factor (soluble CD23) in diseases associated with elevated IgE.

4. Descriptive epidemiology of bronchial reactivity in an adult population: results from a community study.

5. Associations between asthma history, atopy, and non-specific bronchial responsiveness in young adults.

6. Peripheral blood T lymphocytes in seasonal bronchial asthma.

Review 7. Consequences of IgE/CD23-mediated antigen presentation in allergy.

8. CD4 T-lymphocyte activation in acute severe asthma. Relationship to disease severity and atopic status.

9. CD23: a multi-functional receptor/lymphokine?

10. Serum levels of soluble IL-2R, CD4 and CD8 in bronChial asthma.

1. Soluble CD23 controls IgE synthesis and homeostasis in human B cells.

Review 2. Omalizumab and IgE in the Control of Severe Allergic Asthma.

3. Soluble CD23 levels are inversely associated with atopy and parasite-specific IgE levels but not with polyclonal IgE levels in people exposed to helminth infection.