Literature DB >> 18473937

Future target molecules for influenza treatment.

N Uchide1, H Toyoda.   

Abstract

Induction of apoptosis and pro-inflammatory cytokine gene expression in influenza virus-infected cells activates production of toxic superoxide by macrophages. Pyrrolidine dithiocarbamate and nordihydroguaiaretic acid inhibit influenza virus proliferation and scavenge superoxide. These results suggest that they can be potential candidates for a drug of choice for influenza chemotherapy.

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Year:  2008        PMID： 18473937     DOI： 10.2174/138955708784223530

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  7 in total

1.  Therapy of experimental influenza virus infection with pyrrolidine dithiocarbamate.

Authors:  Nadine Wiesener; Christin Zimmer; Nadine Jarasch-Althof; Peter Wutzler; Andreas Henke
Journal:  Med Microbiol Immunol       Date:  2010-12-21       Impact factor: 3.402

2.  Kolaviron Improves Morbidity and Suppresses Mortality by Mitigating Oxido-Inflammation in BALB/c Mice Infected with Influenza Virus.

Authors:  Ifeoluwa O Awogbindin; David O Olaleye; Ebenezer O Farombi
Journal:  Viral Immunol       Date:  2015-07-22       Impact factor: 2.257

Review 3.  Possible roles of proinflammatory and chemoattractive cytokines produced by human fetal membrane cells in the pathology of adverse pregnancy outcomes associated with influenza virus infection.

Authors:  Noboru Uchide; Kunio Ohyama; Toshio Bessho; Makoto Takeichi; Hiroo Toyoda
Journal:  Mediators Inflamm       Date:  2012-07-31       Impact factor: 4.711

4.  Identification of traditional medicinal plant extracts with novel anti-influenza activity.

Authors:  Dhivya Rajasekaran; Enzo A Palombo; Tiong Chia Yeo; Diana Lim Siok Ley; Chu Lee Tu; Francois Malherbe; Lara Grollo
Journal:  PLoS One       Date:  2013-11-27       Impact factor: 3.240

5.  Epimedium koreanum Nakai displays broad spectrum of antiviral activity in vitro and in vivo by inducing cellular antiviral state.

Authors:  Won-Kyung Cho; Prasanna Weeratunga; Byeong-Hoon Lee; Jun-Seol Park; Chul-Joong Kim; Jin Yeul Ma; Jong-Soo Lee
Journal:  Viruses       Date:  2015-01-20       Impact factor: 5.048

Review 6.  Antioxidant therapy as a potential approach to severe influenza-associated complications.

Authors:  Noboru Uchide; Hiroo Toyoda
Journal:  Molecules       Date:  2011-02-28       Impact factor: 4.411

7.  Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice.

Authors:  Guimei He; Changgui Dong; Zhihua Luan; Bronwyn M McAllan; Tong Xu; Lihong Zhao; Jian Qiao
Journal:  Influenza Other Respir Viruses       Date:  2013-01-22       Impact factor: 4.380
  7 in total

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