Literature DB >> 18472946

Cytokine production by human colonic intraepithelial lymphocytes in controls and ulcerative colitis.

P Hoang1, H R Dalton, H J de Silv, D P Jewell.   

Abstract

Using an ELISA technique, concentrations of gamma-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of gamma-interferon and interleukin-2 when stimulated with PHA, but significantly more than when unstimulated (p < 0.05). There was no difference in production of these cytokines by IEL from control or inflammatory bowel disease.

Entities:  

Year:  1994        PMID： 18472946      PMCID： PMC2367034          DOI： 10.1155/S0962935194000311

Source DB:  PubMed          Journal:  Mediators Inflamm        ISSN： 0962-9351            Impact factor:   4.711


  12 in total

Review 1.  Role of cytokines and platelet-activating factor in microvascular immune injury.

Authors:  P Braquet; D Hosford; M Braquet; R Bourgain; F Bussolino
Journal:  Int Arch Allergy Appl Immunol       Date:  1989

Review 2.  PAF/cytokine auto-generated feedback networks in microvascular immune injury: consequences in shock, ischemia and graft rejection.

Authors:  P Braquet; M Paubert-Braquet; R H Bourgain; F Bussolino; D Hosford
Journal:  J Lipid Mediat       Date:  1989 Mar-Apr

3.  Granulocytes, platelet-activating factor, and myocardial injury.

Authors:  R Joseph; K M Welch
Journal:  Circulation       Date:  1989-06       Impact factor: 29.690

4.  Circulating tumour necrosis factor-alpha (cachectin) in myocardial infarction.

Authors:  C P Maury; A M Teppo
Journal:  J Intern Med       Date:  1989-05       Impact factor: 8.989

Review 5.  Platelet activating factor (PAF). A review of its effects, antagonists and possible future clinical implications (Part I).

Authors:  M Koltai; D Hosford; P Guinot; A Esanu; P Braquet
Journal:  Drugs       Date:  1991-07       Impact factor: 9.546

6.  Tumor necrosis factor primes the effects of platelet-activating factor on rat vascular permeability.

Authors:  M G Sirois; G E Plante; P Braquet; P Sirois
Journal:  J Lipid Mediat       Date:  1990

7.  Mechanisms of the cardioprotective actions of WEB-2170, bepafant, a platelet activating factor antagonist, in myocardial ischemia and reperfusion.

Authors:  X L Ma; A S Weyrich; S Krantz; A M Lefer
Journal:  J Pharmacol Exp Ther       Date:  1992-03       Impact factor: 4.030

8.  Inhibitory effect of new PAF antagonists on PAF-induced rabbit platelet aggregation in vitro and ex vivo.

Authors:  T L Yue; R Rabinovici; M Farhat; G Feuerstein
Journal:  J Lipid Mediat       Date:  1991 Jan-Feb

9.  Production and release of platelet-activating factor by the injured heart-muscle cell (cardiomyocyte).

Authors:  D R Janero; C Burghardt
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1990-02

10.  Production and characterization of monoclonal antibodies to human tumor necrosis factor.

Authors:  M Hirai; N Okamura; Y Terano; M Tsujimoto; H Nakazato
Journal:  J Immunol Methods       Date:  1987-01-26       Impact factor: 2.303
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  2 in total

Review 1.  Immunopathology of human inflammatory bowel disease.

Authors:  P Brandtzaeg; G Haraldsen; J Rugtveit
Journal:  Springer Semin Immunopathol       Date:  1997

2.  Human colonic intraepithelial lymphocytes regulate the cytokines produced by lamina propria mononuclear cells.

Authors:  P Hoang; J P Dehennin; L Li; C Sibille; A Geubel; J P Vaerman
Journal:  Mediators Inflamm       Date:  1997       Impact factor: 4.711
  2 in total

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