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Literature DB >> 18472898

1,3,4-thiadiazole derivatives. Part 9. Synthesis and biological activity of metal complexes of 5-(2-aminoethyl)-2-amino-1,3,4-thiadiazole.

M Barboiu¹, M Cimpoesu, C Guran, C T Supuran.

Abstract

Metal complexes of the title ligand (L) containing Co(II), Ni(II) and Cu(II) were prepared and characterized by elemental analysis, IR, electronic spectroscopy and conductimetry. The new derivatives, possessing the following formulae, CuL(2)(OH)(2), NiL(2)Cl(2), and [Co(2)LCl(4)](n) showed in vitro antifungal activity against Aspergillus and Candida spp.

Entities: Chemical

Year: 1996 PMID： 18472898 PMCID： PMC2366233 DOI： 10.1155/MBD.1996.227

Source DB: PubMed Journal: Met Based Drugs ISSN： 0793-0291

3 in total

Review 1. Synthetic methods, chemistry, and the anticonvulsant activity of thiadiazoles.

Authors: Bhawna Sharma; Amita Verma; Sunil Prajapati; Upendra Kumar Sharma
Journal: Int J Med Chem Date: 2013-04-30

Review 2. 2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents.

Authors: Georgeta Serban; Oana Stanasel; Sanda Bota; Eugenia Serban
Journal: Drug Des Devel Ther Date: 2018-05-31 Impact factor: 4.162

3. Crystal structure, spectroscopic characterization and Hirshfeld surface analysis of trans-di-aqua-[2,5-bis-(pyridin-4-yl)-1,3,4-oxa-diazole]di-thio-cyanato-nickel(II).

Authors: Ferdaousse Rhoufal; Fouad Bentiss; Salaheddine Guesmi; El Mostafa Ketatni; Mohamed Saadi; Lahcen El Ammari
Journal: Acta Crystallogr E Crystallogr Commun Date: 2019-06-21

3 in total