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Literature DB >> 1846666

An okadaic acid-sensitive phosphatase negatively controls the cyclin degradation pathway in amphibian eggs.

T Lorca¹, D Fesquet, F Zindy, F Le Bouffant, M Cerruti, C Brechot, G Devauchelle, M Dorée.
1. CNRS, Montpellier, France.

Abstract

Inhibition of okadaic acid-sensitive phosphatases released the cyclin degradation pathway from its inhibited state in extracts prepared from unfertilized Xenopus eggs arrested at the second meiotic metaphase. It also switched on cyclin protease activity in a permanent fashion in interphase extracts prepared from activated eggs. Even after cdc2 kinase inactivation, microinjection of okadaic acid-treated interphase extracts pushed G2-arrested recipient oocytes into the M phase, suggesting that the phosphatase inhibitor stabilizes the activity of an unidentified factor which shares in common with cdc2 kinase the maturation-promoting factor activity.

Entities: Chemical Gene Species

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Year: 1991 PMID： 1846666 PMCID： PMC359804 DOI： 10.1128/mcb.11.2.1171-1175.1991

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

26 in total

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Authors: J C Labbe; A Picard; G Peaucellier; J C Cavadore; P Nurse; M Doree
Journal: Cell Date: 1989-04-21 Impact factor: 41.582

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Authors: N Standart; J Minshull; J Pines; T Hunt
Journal: Dev Biol Date: 1987-11 Impact factor: 3.582

3. The cyclin B2 component of MPF is a substrate for the c-mos(xe) proto-oncogene product.

Authors: L M Roy; B Singh; J Gautier; R B Arlinghaus; S K Nordeen; J L Maller
Journal: Cell Date: 1990-06-01 Impact factor: 41.582

4. Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes.

Authors: J Goris; J Hermann; P Hendrix; R Ozon; W Merlevede
Journal: FEBS Lett Date: 1989-03-13 Impact factor: 4.124

5. The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs.

Authors: N Sagata; N Watanabe; G F Vande Woude; Y Ikawa
Journal: Nature Date: 1989-11-30 Impact factor: 49.962

6. Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase.

Authors: M A Félix; J C Labbé; M Dorée; T Hunt; E Karsenti
Journal: Nature Date: 1990-07-26 Impact factor: 49.962

7. Xenopus homolog of the mos protooncogene transforms mammalian fibroblasts and induces maturation of Xenopus oocytes.

Authors: R S Freeman; K M Pickham; J P Kanki; B A Lee; S V Pena; D J Donoghue
Journal: Proc Natl Acad Sci U S A Date: 1989-08 Impact factor: 11.205

8. Cyclin is a component of maturation-promoting factor from Xenopus.

Authors: J Gautier; J Minshull; M Lohka; M Glotzer; T Hunt; J L Maller
Journal: Cell Date: 1990-02-09 Impact factor: 41.582

9. Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma.

Authors: J Wang; X Chenivesse; B Henglein; C Bréchot
Journal: Nature Date: 1990-02-08 Impact factor: 49.962

10. Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid.

Authors: M A Félix; P Cohen; E Karsenti
Journal: EMBO J Date: 1990-03 Impact factor: 11.598

25 in total

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Authors: D H Walker; A A DePaoli-Roach; J L Maller
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4. A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase.

Authors: A Goldbeter
Journal: Proc Natl Acad Sci U S A Date: 1991-10-15 Impact factor: 11.205

5. A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

Authors: Qiju Wu; Yanxiang Guo; Ayumi Yamada; Jennifer A Perry; Michael Z Wang; Marito Araki; Christopher D Freel; Jeffrey J Tung; Wanli Tang; Seth S Margolis; Peter K Jackson; Hiroyuki Yamano; Maki Asano; Sally Kornbluth
Journal: Curr Biol Date: 2007-02-06 Impact factor: 10.834

6. The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase.

Authors: M Brandeis; T Hunt
Journal: EMBO J Date: 1996-10-01 Impact factor: 11.598

7. Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.

Authors: S Lahav-Baratz; V Sudakin; J V Ruderman; A Hershko
Journal: Proc Natl Acad Sci U S A Date: 1995-09-26 Impact factor: 11.205

8. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.

Authors: V Sudakin; D Ganoth; A Dahan; H Heller; J Hershko; F C Luca; J V Ruderman; A Hershko
Journal: Mol Biol Cell Date: 1995-02 Impact factor: 4.138

9. Mitotic arrest caused by the amino terminus of Xenopus cyclin B2.

Authors: H M van der Velden; M J Lohka
Journal: Mol Cell Biol Date: 1993-03 Impact factor: 4.272

10. Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis.

Authors: H Ronne; M Carlberg; G Z Hu; J O Nehlin
Journal: Mol Cell Biol Date: 1991-10 Impact factor: 4.272