Literature DB >> 18463152

A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters.

Elaine W Lamirande1, Marta L DeDiego, Anjeanette Roberts, Jadon P Jackson, Enrique Alvarez, Tim Sheahan, Wun-Ju Shieh, Sherif R Zaki, Ralph Baric, Luis Enjuanes, Kanta Subbarao.   

Abstract

The immunogenicity and protective efficacy of a live attenuated vaccine consisting of a recombinant severe acute respiratory syndrome (SARS) coronavirus lacking the E gene (rSARS-CoV-DeltaE) were studied using hamsters. Hamsters immunized with rSARS-CoV-DeltaE developed high serum-neutralizing antibody titers and were protected from replication of homologous (SARS-CoV Urbani) and heterologous (GD03) SARS-CoV in the upper and lower respiratory tract. rSARS-CoV-DeltaE-immunized hamsters remained active following wild-type virus challenge, while mock-immunized hamsters displayed decreased activity. Despite being attenuated in replication in the respiratory tract, rSARS-CoV-DeltaE is an immunogenic and efficacious vaccine in hamsters.

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Year:  2008        PMID： 18463152      PMCID： PMC2493341          DOI： 10.1128/JVI.00304-08

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  11 in total

1.  Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters.

Authors:  Anjeanette Roberts; Leatrice Vogel; Jeannette Guarner; Norman Hayes; Brian Murphy; Sherif Zaki; Kanta Subbarao
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

2.  Bats are natural reservoirs of SARS-like coronaviruses.

Authors:  Wendong Li; Zhengli Shi; Meng Yu; Wuze Ren; Craig Smith; Jonathan H Epstein; Hanzhong Wang; Gary Crameri; Zhihong Hu; Huajun Zhang; Jianhong Zhang; Jennifer McEachern; Hume Field; Peter Daszak; Bryan T Eaton; Shuyi Zhang; Lin-Fa Wang
Journal:  Science       Date:  2005-09-29       Impact factor: 47.728

3.  Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats.

Authors:  Susanna K P Lau; Patrick C Y Woo; Kenneth S M Li; Yi Huang; Hoi-Wah Tsoi; Beatrice H L Wong; Samson S Y Wong; Suet-Yi Leung; Kwok-Hung Chan; Kwok-Yung Yuen
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-16       Impact factor: 11.205

4.  Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.

Authors:  Fernando Almazán; Marta L Dediego; Carmen Galán; David Escors; Enrique Alvarez; Javier Ortego; Isabel Sola; Sonia Zuñiga; Sara Alonso; Jose L Moreno; Aitor Nogales; Carmen Capiscol; Luis Enjuanes
Journal:  J Virol       Date:  2006-08-23       Impact factor: 5.103

5.  A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo.

Authors:  Marta L DeDiego; Enrique Alvarez; Fernando Almazán; María Teresa Rejas; Elaine Lamirande; Anjeanette Roberts; Wun-Ju Shieh; Sherif R Zaki; Kanta Subbarao; Luis Enjuanes
Journal:  J Virol       Date:  2006-11-15       Impact factor: 5.103

6.  Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice.

Authors:  Kanta Subbarao; Josephine McAuliffe; Leatrice Vogel; Gary Fahle; Steven Fischer; Kathleen Tatti; Michelle Packard; Wun-Ju Shieh; Sherif Zaki; Brian Murphy
Journal:  J Virol       Date:  2004-04       Impact factor: 5.103

7.  Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.

Authors:  Y Guan; B J Zheng; Y Q He; X L Liu; Z X Zhuang; C L Cheung; S W Luo; P H Li; L J Zhang; Y J Guan; K M Butt; K L Wong; K W Chan; W Lim; K F Shortridge; K Y Yuen; J S M Peiris; L L M Poon
Journal:  Science       Date:  2003-09-04       Impact factor: 47.728

8.  Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants.

Authors:  Damon Deming; Timothy Sheahan; Mark Heise; Boyd Yount; Nancy Davis; Amy Sims; Mehul Suthar; Jack Harkema; Alan Whitmore; Raymond Pickles; Ande West; Eric Donaldson; Kristopher Curtis; Robert Johnston; Ralph Baric
Journal:  PLoS Med       Date:  2006-12       Impact factor: 11.069

9.  Animal models and vaccines for SARS-CoV infection.

Authors:  Anjeanette Roberts; Elaine W Lamirande; Leatrice Vogel; Jadon P Jackson; Christopher D Paddock; Jeannette Guarner; Sherif R Zaki; Timothy Sheahan; Ralph Baric; Kanta Subbarao
Journal:  Virus Res       Date:  2007-05-11       Impact factor: 3.303

10.  An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

Authors:  Elisabetta Traggiai; Stephan Becker; Kanta Subbarao; Larissa Kolesnikova; Yasushi Uematsu; Maria Rita Gismondo; Brian R Murphy; Rino Rappuoli; Antonio Lanzavecchia
Journal:  Nat Med       Date:  2004-07-11       Impact factor: 53.440
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  74 in total

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Authors:  Naoko Iwata-Yoshikawa; Akihiko Uda; Tadaki Suzuki; Yasuko Tsunetsugu-Yokota; Yuko Sato; Shigeru Morikawa; Masato Tashiro; Tetsutaro Sata; Hideki Hasegawa; Noriyo Nagata
Journal:  J Virol       Date:  2014-05-21       Impact factor: 5.103

2.  Channel-Inactivating Mutations and Their Revertant Mutants in the Envelope Protein of Infectious Bronchitis Virus.

Authors:  Janet To; Wahyu Surya; To Sing Fung; Yan Li; Carmina Verdià-Bàguena; Maria Queralt-Martin; Vicente M Aguilella; Ding Xiang Liu; Jaume Torres
Journal:  J Virol       Date:  2017-02-14       Impact factor: 5.103

3.  Immunogenicity and protective efficacy in mice and hamsters of a β-propiolactone inactivated whole virus SARS-CoV vaccine.

Authors:  Anjeanette Roberts; Elaine W Lamirande; Leatrice Vogel; Benoît Baras; Geneviève Goossens; Isabelle Knott; Jun Chen; Jerrold M Ward; Ventzislav Vassilev; Kanta Subbarao
Journal:  Viral Immunol       Date:  2010-10       Impact factor: 2.257

Review 4.  Coronavirus Disease 2019-COVID-19.

Authors:  Kuldeep Dhama; Sharun Khan; Ruchi Tiwari; Shubhankar Sircar; Sudipta Bhat; Yashpal Singh Malik; Karam Pal Singh; Wanpen Chaicumpa; D Katterine Bonilla-Aldana; Alfonso J Rodriguez-Morales
Journal:  Clin Microbiol Rev       Date:  2020-06-24       Impact factor: 26.132

Review 5.  Coronavirus pathogenesis.

Authors:  Susan R Weiss; Julian L Leibowitz
Journal:  Adv Virus Res       Date:  2011       Impact factor: 9.937

6.  Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates.

Authors:  Jose A Regla-Nava; Jose L Nieto-Torres; Jose M Jimenez-Guardeño; Raul Fernandez-Delgado; Craig Fett; Carlos Castaño-Rodríguez; Stanley Perlman; Luis Enjuanes; Marta L DeDiego
Journal:  J Virol       Date:  2015-01-21       Impact factor: 5.103

Review 7.  Counting on COVID-19 Vaccine: Insights into the Current Strategies, Progress and Future Challenges.

Authors:  Ramesh Kandimalla; Pratik Chakraborty; Jayalakshmi Vallamkondu; Anupama Chaudhary; Sonalinandini Samanta; P Hemachandra Reddy; Vincenzo De Feo; Saikat Dewanjee
Journal:  Biomedicines       Date:  2021-11-22

8.  A single tyrosine in the severe acute respiratory syndrome coronavirus membrane protein cytoplasmic tail is important for efficient interaction with spike protein.

Authors:  Corrin E McBride; Carolyn E Machamer
Journal:  J Virol       Date:  2009-12-09       Impact factor: 5.103

9.  Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival.

Authors:  Marta L DeDiego; Jose L Nieto-Torres; Jose A Regla-Nava; Jose M Jimenez-Guardeño; Raul Fernandez-Delgado; Craig Fett; Carlos Castaño-Rodriguez; Stanley Perlman; Luis Enjuanes
Journal:  J Virol       Date:  2013-11-06       Impact factor: 5.103

10.  Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein.

Authors:  Craig Fett; Marta L DeDiego; Jose A Regla-Nava; Luis Enjuanes; Stanley Perlman
Journal:  J Virol       Date:  2013-04-10       Impact factor: 5.103
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