Literature DB >> 16195424

Bats are natural reservoirs of SARS-like coronaviruses.

Wendong Li1, Zhengli Shi, Meng Yu, Wuze Ren, Craig Smith, Jonathan H Epstein, Hanzhong Wang, Gary Crameri, Zhihong Hu, Huajun Zhang, Jianhong Zhang, Jennifer McEachern, Hume Field, Peter Daszak, Bryan T Eaton, Shuyi Zhang, Lin-Fa Wang.   

Abstract

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.

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Year:  2005        PMID: 16195424     DOI: 10.1126/science.1118391

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  1064 in total

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Journal:  J Virol       Date:  2011-09-21       Impact factor: 5.103

2.  Type III IFNs in pteropid bats: differential expression patterns provide evidence for distinct roles in antiviral immunity.

Authors:  Peng Zhou; Chris Cowled; Shawn Todd; Gary Crameri; Elena R Virtue; Glenn A Marsh; Reuben Klein; Zhengli Shi; Lin-Fa Wang; Michelle L Baker
Journal:  J Immunol       Date:  2011-01-28       Impact factor: 5.422

3.  Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation.

Authors:  Arun K Ghosh; Jun Takayama; Kalapala Venkateswara Rao; Kiira Ratia; Rima Chaudhuri; Debbie C Mulhearn; Hyun Lee; Daniel B Nichols; Surendranath Baliji; Susan C Baker; Michael E Johnson; Andrew D Mesecar
Journal:  J Med Chem       Date:  2010-07-08       Impact factor: 7.446

4.  Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes.

Authors:  Hui Hui Wong; Pankaj Kumar; Felicia Pei Ling Tay; Dimitri Moreau; Ding Xiang Liu; Frédéric Bard
Journal:  J Virol       Date:  2015-08-26       Impact factor: 5.103

Review 5.  Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases.

Authors:  Rita M Meganck; Ralph S Baric
Journal:  Nat Med       Date:  2021-03-15       Impact factor: 53.440

6.  The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles.

Authors:  Scott R Schaecher; Jason M Mackenzie; Andrew Pekosz
Journal:  J Virol       Date:  2006-11-01       Impact factor: 5.103

7.  Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus.

Authors:  Paul B McCray; Lecia Pewe; Christine Wohlford-Lenane; Melissa Hickey; Lori Manzel; Lei Shi; Jason Netland; Hong Peng Jia; Carmen Halabi; Curt D Sigmund; David K Meyerholz; Patricia Kirby; Dwight C Look; Stanley Perlman
Journal:  J Virol       Date:  2006-11-01       Impact factor: 5.103

Review 8.  Structure, Function, and Evolution of Coronavirus Spike Proteins.

Authors:  Fang Li
Journal:  Annu Rev Virol       Date:  2016-08-25       Impact factor: 10.431

9.  Handling Stress and Sample Storage Are Associated with Weaker Complement-Mediated Bactericidal Ability in Birds but Not Bats.

Authors:  Daniel J Becker; Gábor Á Czirják; Agnieszka Rynda-Apple; Raina K Plowright
Journal:  Physiol Biochem Zool       Date:  2019 Jan/Feb       Impact factor: 2.247

10.  Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2.

Authors:  Naoko Yoshikawa; Tomoki Yoshikawa; Terence Hill; Cheng Huang; Douglas M Watts; Shinji Makino; Gregg Milligan; Tehsheng Chan; Clarence J Peters; Chien-Te K Tseng
Journal:  J Virol       Date:  2009-03-18       Impact factor: 5.103

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