Literature DB >> 18462105

Impact of lactoferrin supplementation on growth and prevalence of Giardia colonization in children.

Theresa J Ochoa1, Elsa Chea-Woo, Miguel Campos, Iris Pecho, Ana Prada, Robert J McMahon, Thomas G Cleary.   

Abstract

We conducted a randomized, double-blind, placebo-controlled trial comparing supplementation with bovine lactoferrin versus placebo for the prevention of diarrhea in children. Comparison of overall diarrhea incidence and prevalence rates found no significant difference between the 2 groups. However, there was a lower prevalence of colonization with Giardia species and better growth among children in the lactoferrin group.

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Year:  2008        PMID: 18462105      PMCID: PMC2440650          DOI: 10.1086/588476

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  10 in total

Review 1.  Lactoferrin--a multifunctional protein with antimicrobial properties.

Authors:  Sebastien Farnaud; Robert W Evans
Journal:  Mol Immunol       Date:  2003-11       Impact factor: 4.407

2.  Efficacy of rice-based oral rehydration solution containing recombinant human lactoferrin and lysozyme in Peruvian children with acute diarrhea.

Authors:  Nelly Zavaleta; Dante Figueroa; Juan Rivera; Julia Sánchez; Segundo Alfaro; Bo Lönnerdal
Journal:  J Pediatr Gastroenterol Nutr       Date:  2007-02       Impact factor: 2.839

3.  Giardicidal activity of lactoferrin and N-terminal peptides.

Authors:  J M Turchany; S B Aley; F D Gillin
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

4.  Ultrastructural effects of lactoferrin binding on Giardia lamblia trophozoites.

Authors:  J M Turchany; J M McCaffery; S B Aley; F D Gillin
Journal:  J Eukaryot Microbiol       Date:  1997 Jan-Feb       Impact factor: 3.346

5.  Effect of lactoferrin on enteroaggregative E. coli (EAEC).

Authors:  Theresa J Ochoa; Eric L Brown; Chase E Guion; Jane Z Chen; Robert J McMahon; Thomas G Cleary
Journal:  Biochem Cell Biol       Date:  2006-06       Impact factor: 3.626

6.  Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis.

Authors:  Henry F Gomez; Theresa J Ochoa; Irene Herrera-Insua; Lily G Carlin; Thomas G Cleary
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

7.  Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study.

Authors:  Douglas S Berkman; Andres G Lescano; Robert H Gilman; Sonia L Lopez; Maureen M Black
Journal:  Lancet       Date:  2002-02-16       Impact factor: 79.321

8.  Lactoferrin impairs type III secretory system function in enteropathogenic Escherichia coli.

Authors:  Theresa J Ochoa; Marita Noguera-Obenza; Frank Ebel; Carlos A Guzman; Henry F Gomez; Thomas G Cleary
Journal:  Infect Immun       Date:  2003-09       Impact factor: 3.441

9.  Iron status of infants fed low-iron formula: no effect of added bovine lactoferrin or nucleotides.

Authors:  Olle Hernell; Bo Lönnerdal
Journal:  Am J Clin Nutr       Date:  2002-10       Impact factor: 7.045

10.  Supplementation of an adapted formula with bovine lactoferrin. 2. Effects on serum iron, ferritin and zinc levels.

Authors:  R Chierici; G Sawatzki; L Tamisari; S Volpato; V Vigi
Journal:  Acta Paediatr       Date:  1992 Jun-Jul       Impact factor: 2.299

  10 in total
  19 in total

1.  Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children.

Authors:  Theresa J Ochoa; Elsa Chea-Woo; Nelly Baiocchi; Iris Pecho; Miguel Campos; Ana Prada; Gladys Valdiviezo; Angela Lluque; Dejian Lai; Thomas G Cleary
Journal:  J Pediatr       Date:  2012-08-30       Impact factor: 4.406

Review 2.  Clinical research review: usefulness of bovine lactoferrin in child health.

Authors:  Momoko Miyakawa; Hirotsugu Oda; Miyuki Tanaka
Journal:  Biometals       Date:  2022-08-09       Impact factor: 3.378

Review 3.  Effect of lactoferrin on enteric pathogens.

Authors:  Theresa J Ochoa; Thomas G Cleary
Journal:  Biochimie       Date:  2008-04-18       Impact factor: 4.079

4.  Travelers' diarrhea: an update on susceptibility, prevention, and treatment.

Authors:  Miguel M Cabada; A Clinton White
Journal:  Curr Gastroenterol Rep       Date:  2008-10

5.  The Role of Maternal Breast Milk in Preventing Infantile Diarrhea in the Developing World.

Authors:  Christie G Turin; Theresa J Ochoa
Journal:  Curr Trop Med Rep       Date:  2014-06-01

Review 6.  Mini-review: Lactoferrin: a bioinspired, anti-biofilm therapeutic.

Authors:  M C Ammons; V Copié
Journal:  Biofouling       Date:  2013       Impact factor: 3.209

7.  Protection against diarrhea associated with Giardia intestinalis Is lost with multi-nutrient supplementation: a study in Tanzanian children.

Authors:  Jacobien Veenemans; Theo Mank; Maarten Ottenhof; Amrish Baidjoe; Erasto V Mbugi; Ayse Y Demir; Jos P M Wielders; Huub F J Savelkoul; Hans Verhoef
Journal:  PLoS Negl Trop Dis       Date:  2011-06-07

8.  High prevalence of Giardia duodenalis Assemblage B infection and association with underweight in Rwandan children.

Authors:  Ralf Ignatius; Jean Bosco Gahutu; Christian Klotz; Christian Steininger; Cyprien Shyirambere; Michel Lyng; Andre Musemakweri; Toni Aebischer; Peter Martus; Gundel Harms; Frank P Mockenhaupt
Journal:  PLoS Negl Trop Dis       Date:  2012-06-12

Review 9.  Advances in understanding Giardia: determinants and mechanisms of chronic sequelae.

Authors:  Luther A Bartelt; R Balfour Sartor
Journal:  F1000Prime Rep       Date:  2015-05-26

10.  Human milk immunomodulatory proteins are related to development of infant body composition during the first year of lactation.

Authors:  Zoya Gridneva; Ching T Lai; Alethea Rea; Wan J Tie; Leigh C Ward; Kevin Murray; Peter E Hartmann; Donna T Geddes
Journal:  Pediatr Res       Date:  2020-05-21       Impact factor: 3.756

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