Literature DB >> 18459147

Role of homeobox genes in the patterning, specification, and differentiation of ectodermal appendages in mammals.

Olivier Duverger1, Maria I Morasso.   

Abstract

Homeobox genes are an evolutionarily conserved class of transcription factors that are key regulators during developmental processes such as regional specification, patterning, and differentiation. In this review, we summarize the expression pattern, loss- and/or gain-of-function mouse models, and naturally occurring mouse and human mutations of known homeobox genes required for the development of ectodermal appendages. (c) 2008 Wiley-Liss, Inc.

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Year:  2008        PMID: 18459147      PMCID: PMC2561923          DOI: 10.1002/jcp.21491

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN: 0021-9541            Impact factor:   6.384


  113 in total

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Authors:  S Vainio; I Karavanova; A Jowett; I Thesleff
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7.  A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis.

Authors:  E W Jabs; U Müller; X Li; L Ma; W Luo; I S Haworth; I Klisak; R Sparkes; M L Warman; J B Mulliken
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Authors:  R Quiring; U Walldorf; U Kloter; W J Gehring
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Authors:  K Raju; S Tang; I D Dubé; S Kamel-Reid; D M Bryce; M L Breitman
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  31 in total

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9.  Depletion of MEIS2 inhibits osteogenic differentiation potential of human dental stem cells.

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10.  NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.

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