Literature DB >> 18458990

Post-partum sacral fracture associated with heparin treatment.

Vincent Goëb1, Victor Strotz, Mathieu Verdet, Xavier Le Loët, Olivier Vittecoq.   

Abstract

We report the case of a 19-year-old woman who consulted for low-back pain 3 weeks after her first delivery. This young woman had a personal history of protein C deficiency and was treated daily during her pregnancy with low-molecular-weight heparin. Her body mass index was 34 and she only gained 10 kg during her pregnancy. Since the delivery - which occurred without any complication - she had suffered from a gradually increasing right-buttock pain and limp. Magnetic resonance imaging (MRI) revealed a fracture of the right sacral ala. After analgesia and 1 month of home relative bed rest, the patient recovered her functional capacities. Regarding our patient, who had no potential clinical risk factors for osteoporosis, the causal effect of heparin is thus possible but not certain. This case report illustrates the fact that clinicians should have a high suspicion of pelvic fracture in post-partum women, even in very young ones, presenting sudden onset of low back and pelvic pain, especially when they have received heparin during pregnancy. MRI seems to be the key exam because it is able to detect and stage fractures or microfractures.

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Year:  2008        PMID: 18458990     DOI: 10.1007/s10067-008-0898-9

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  15 in total

1.  Bilateral fracture of the sacrum associated with pregnancy: a case report.

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Journal:  Osteoporos Int       Date:  1999       Impact factor: 4.507

2.  Transverse sacral fracture with transient neurologic complication.

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Review 3.  Sacral insufficiency fractures: current concepts of management.

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Journal:  Osteoporos Int       Date:  2006-07-20       Impact factor: 4.507

Review 4.  Safety profile of different low-molecular weight heparins used at therapeutic dose.

Authors:  Isabelle Gouin-Thibault; Eric Pautas; Virginie Siguret
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

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Authors:  B Oliveri; C Gomez Acotto; C Mautalen
Journal:  Rev Rhum Engl Ed       Date:  1999-10

6.  Magnetic resonance imaging in osteomalacic insufficiency fractures of the pelvis.

Authors:  K Kanberoglu; F Kantarci; D Cebi; M H Yilmaz; S Kurugoglu; A Bilici; H Koyuncu
Journal:  Clin Radiol       Date:  2005-01       Impact factor: 2.350

Review 7.  Sacral insufficiency fracture.

Authors:  S P Blake; A M Connors
Journal:  Br J Radiol       Date:  2004-10       Impact factor: 3.039

8.  Home-based resistance training improves femoral bone mineral density in women on hormone therapy.

Authors:  James Oat Judge; Alison Kleppinger; Anne Kenny; Jo-Anne Smith; Brad Biskup; Glenn Marcella
Journal:  Osteoporos Int       Date:  2005-03-08       Impact factor: 4.507

Review 9.  Biophysical stimulation of bone fracture repair, regeneration and remodelling.

Authors:  Edmund Y S Chao; Nozomu Inoue
Journal:  Eur Cell Mater       Date:  2003-12-31       Impact factor: 3.942

10.  Sacral stress fracture in a female collegiate distance runner: a case report.

Authors:  D Klossner
Journal:  J Athl Train       Date:  2000-10       Impact factor: 2.860

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  7 in total

1.  Postpartum bilateral sacral stress fracture without osteoporosis-a case report and literature review.

Authors:  Y F Wu; K Lu; C Girgis; M Preda; V Preda
Journal:  Osteoporos Int       Date:  2021-01-13       Impact factor: 4.507

2.  Postpartum osteoporosis and vertebral fractures in two patients treated with enoxaparin during pregnancy.

Authors:  D Ozdemir; A A Tam; A Dirikoc; R Ersoy; B Cakir
Journal:  Osteoporos Int       Date:  2014-08-20       Impact factor: 4.507

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4.  Severe postpartum osteoporosis with increased PTHrP during lactation in a patient after total thyroidectomy and parathyroidectomy.

Authors:  E Segal; I Hochberg; Y Weisman; S Ish-Shalom
Journal:  Osteoporos Int       Date:  2011-01-18       Impact factor: 4.507

5.  The Effect of Low Molecular Weight Heparins on Fracture Healing.

Authors:  Stylianos Kapetanakis; Evangelos Nastoulis; Theano Demesticha; Thespis Demetriou
Journal:  Open Orthop J       Date:  2015-06-26

6.  Postpartum sacral fracture in a 30-year-old female.

Authors:  Rebecca L Roller; Eric A Walker; Scott W Michelitch
Journal:  Radiol Case Rep       Date:  2015-12-07

7.  An Atraumatic Sacral Fracture with Lumbosacral Radiculopathy Complicating the Early Postpartum Period: A Case Report.

Authors:  Jacques A J Malherbe; Sue Davel
Journal:  Am J Case Rep       Date:  2019-06-06
  7 in total

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