STUDY DESIGN: Biomechanical study. OBJECTIVE: To test 2 different intervertebral positions of a semilunar cage and their effects on 3-dimensional stability and segmental lordosis in a model of transforaminal lumbar interbody fusion (TLIF). SUMMARY OF BACKGROUND DATA: In his original TLIF description, Harms recommended decortication of endplates, followed by placement of mesh cages in the middle-posterior intervertebral third. Subsequent studies presented conflicting recommendations: anterior placement of the spacer-cage for better load-sharing versus placement on the stronger posterolateral endplate regions. METHODS:Six human lumbar spinal functional units were first tested intact. TLIF was performed using a semilunar poly-ether-ether-ketone cage randomly inserted in the anterior (TLIF-A) or posterior (TLIF-P) disc space. Pedicle screws and rods were added. Unconstrained pure moments in axial-torsion, lateral-bending (LB), and flexion-extension (FE) were applied under 0.05 Hz and +/-5 Nm sinusoidal waveform. Segmental motions were recorded. Range of motion (ROM) and neutral zone (NZ) were calculated. Pairwise comparisons were made using nonparametric Wilcoxon-matched pairs signed rank sum test with statistical significance set at P<0.05. RESULTS:TLIF-A and TLIF-P significantly decreased ROM (P<0.05) of the intact spinal functional unit, in FE and LB. In axial-torsion, decrease of ROM after TLIF procedures was not significant (P>0.05). Delta-ROM between TLIF-A and TLIF-P was not significant (P>0.05). TLIF-A and TLIF-P significantly decreased NZ in LB (P<0.05). In FE, TLIF-P significantly decreased NZ (P<0.05); TLIF-A showed a trend toward significance (P=0.09). Delta-NZ between TLIF-A and TLIF-P was not significant (P>0.05). Segmental lordosis of TLIF-A and TLIF-P on C-arm views showed angle differences within the range of measurement error of Cobb angles. CONCLUSIONS: Difference in ROM and NZ between anterior (TLIF-A) or posterior (TLIF-P) positions was not statistically significant. Similarly, both positions did not influence segmental lordosis.
RCT Entities:
STUDY DESIGN: Biomechanical study. OBJECTIVE: To test 2 different intervertebral positions of a semilunar cage and their effects on 3-dimensional stability and segmental lordosis in a model of transforaminal lumbar interbody fusion (TLIF). SUMMARY OF BACKGROUND DATA: In his original TLIF description, Harms recommended decortication of endplates, followed by placement of mesh cages in the middle-posterior intervertebral third. Subsequent studies presented conflicting recommendations: anterior placement of the spacer-cage for better load-sharing versus placement on the stronger posterolateral endplate regions. METHODS: Six human lumbar spinal functional units were first tested intact. TLIF was performed using a semilunar poly-ether-ether-ketone cage randomly inserted in the anterior (TLIF-A) or posterior (TLIF-P) disc space. Pedicle screws and rods were added. Unconstrained pure moments in axial-torsion, lateral-bending (LB), and flexion-extension (FE) were applied under 0.05 Hz and +/-5 Nm sinusoidal waveform. Segmental motions were recorded. Range of motion (ROM) and neutral zone (NZ) were calculated. Pairwise comparisons were made using nonparametric Wilcoxon-matched pairs signed rank sum test with statistical significance set at P<0.05. RESULTS: TLIF-A and TLIF-P significantly decreased ROM (P<0.05) of the intact spinal functional unit, in FE and LB. In axial-torsion, decrease of ROM after TLIF procedures was not significant (P>0.05). Delta-ROM between TLIF-A and TLIF-P was not significant (P>0.05). TLIF-A and TLIF-P significantly decreased NZ in LB (P<0.05). In FE, TLIF-P significantly decreased NZ (P<0.05); TLIF-A showed a trend toward significance (P=0.09). Delta-NZ between TLIF-A and TLIF-P was not significant (P>0.05). Segmental lordosis of TLIF-A and TLIF-P on C-arm views showed angle differences within the range of measurement error of Cobb angles. CONCLUSIONS: Difference in ROM and NZ between anterior (TLIF-A) or posterior (TLIF-P) positions was not statistically significant. Similarly, both positions did not influence segmental lordosis.
Authors: Alejandro D Castellvi; Shankar K Thampi; Daniel J Cook; Matthew S Yeager; Yuan Yao; Qing Zou; Donald M Whiting; Michael Y Oh; Edward R Prostko; Boyle C Cheng Journal: Int J Spine Surg Date: 2015-07-17
Authors: Christopher K Kepler; Russel C Huang; Amit K Sharma; Dennis S Meredith; Ochuko Metitiri; Andrew A Sama; Federico P Girardi; Frank P Cammisa Journal: Orthop Surg Date: 2012-05 Impact factor: 2.071