Literature DB >> 18458584

Fusion rates and SF-36 outcomes after multilevel laminectomy and noninstrumented lumbar fusions in a predominantly geriatric population.

Nancy E Epstein1.   

Abstract

STUDY
DESIGN: This study prospectively analyzed posterolateral fusion rates and Short-Form 36 (SF-36) outcomes after multilevel lumbar laminectomies and noninstrumented fusions.
OBJECTIVE: SF-36 outcomes and posterolateral fusion rates were assessed. SUMMARY OF BACKGROUND DATA: Technologically advanced and expensive instrumentation techniques and fusion adjuncts (ie, bone morphogenetic protein) may not be necessary to achieve lumbar fusion in the geriatric population. Rather, noninstrumented fusions using lamina autograft and a bone volume expander may suffice.
METHODS: Seventy-five patients averaging 69 years of age (49 females, 26 males) underwent average 4.9 level lumbar laminectomies with average 2.0 level noninstrumented posterolateral fusions using lamina autograft (average 30 cm) supplemented with demineralized bone matrix (average 30 cm) in a 50:50 mix. Two independent radiologists separately evaluated both 2-dimensional computed tomography (2D-CT) and dynamic x-ray data 3, 4.5, 6, and up to 12 months postoperatively; patients had to demonstrate fusion on both studies. Outcomes were assessed using the SF-36 questionnaire (preoperatively) 3, 6, 12, and 24 months postoperatively. Patients were followed an average of 3.3 years (minimum 2 y).
RESULTS: Thirteen (17.3%) patients demonstrated pseudarthrosis as they had not fused on dynamic x-ray and/or 2D-CT studies an average of 5.6 months postoperatively. One patient required a secondary fusion. One and 2 years postoperatively, patients demonstrated nearly identical maximal improvement on 6 SF-36 Health Scales, but showed no real changes on General Health and Mental Health scales.
CONCLUSIONS: Seventy-five predominantly geriatric patients underwent multilevel laminectomies with noninstrumented fusions using lamina autograft combined with a bone volume expander. Thirteen patients (17.3%) demonstrated pseudarthrosis on the basis of both dynamic x-ray and 2D-CT criteria; 1 patient required a second instrumented fusion. Moderate pseudarthrosis rates, a low reoperation rate, and satisfactory SF-36 outcomes were achieved using noninstrumented posterolateral fusions in a predominantly geriatric population.

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Mesh:

Year:  2008        PMID: 18458584     DOI: 10.1097/BSD.0b013e318074ddaa

Source DB:  PubMed          Journal:  J Spinal Disord Tech        ISSN: 1536-0652


  9 in total

1.  The efficacy of rhBMP-2 versus autograft for posterolateral lumbar spine fusion in elderly patients.

Authors:  Kwang-Bok Lee; Cyrus E Taghavi; Margaret S Hsu; Kyung-Jin Song; Jeong Hyun Yoo; Gun Keorochana; Stephanie S Ngo; Jeffrey C Wang
Journal:  Eur Spine J       Date:  2009-12-30       Impact factor: 3.134

2.  Bone substitutes and expanders in Spine Surgery: A review of their fusion efficacies.

Authors:  Abhijeet Kadam; Paul W Millhouse; Christopher K Kepler; Kris E Radcliff; Michael G Fehlings; Michael E Janssen; Rick C Sasso; James J Benedict; Alexander R Vaccaro
Journal:  Int J Spine Surg       Date:  2016-09-22

Review 3.  Use of demineralized bone matrix in spinal fusion.

Authors:  Konstantinos Tilkeridis; Panagiotis Touzopoulos; Athanasios Ververidis; Sotirios Christodoulou; Konstantinos Kazakos; Georgios I Drosos
Journal:  World J Orthop       Date:  2014-01-18

4.  Mid-range outcomes in 64 consecutive cases of multilevel fusion for degenerative diseases of the lumbar spine.

Authors:  Marc Röllinghoff; Klaus Schlüter-Brust; Daniel Groos; Rolf Sobottke; Joern William-Patrick Michael; Peer Eysel; Karl Stefan Delank
Journal:  Orthop Rev (Pavia)       Date:  2010-03-20

5.  Clinical and radiographic outcomes of extreme lateral approach to interbody fusion with β-tricalcium phosphate and hydroxyapatite composite for lumbar degenerative conditions.

Authors:  W Blake Rodgers; Edward J Gerber; Jody A Rodgers
Journal:  Int J Spine Surg       Date:  2012-12-01

6.  Low reoperation rate following 336 multilevel lumbar laminectomies with noninstrumented fusions.

Authors:  Nancy Ellen Epstein
Journal:  Surg Neurol Int       Date:  2016-05-17

7.  A review: Reduced reoperation rate for multilevel lumbar laminectomies with noninstrumented versus instrumented fusions.

Authors:  Nancy Ellen Epstein
Journal:  Surg Neurol Int       Date:  2016-05-17

8.  High lumbar noninstrumented fusion rates using lamina autograft and Nanoss/bone marrow aspirate.

Authors:  Nancy E Epstein
Journal:  Surg Neurol Int       Date:  2017-07-20

Review 9.  Allograft Versus Demineralized Bone Matrix in Instrumented and Noninstrumented Lumbar Fusion: A Systematic Review.

Authors:  Zorica Buser; Darrel S Brodke; Jim A Youssef; Elke Rometsch; Jong-Beom Park; S Tim Yoon; Jeffrey C Wang; Hans-Joerg Meisel
Journal:  Global Spine J       Date:  2017-10-25
  9 in total

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