Literature DB >> 18455687

Novel approaches for the treatment of rheumatoid arthritis: lessons from the evaluation of synovial biomarkers in clinical trials.

Daniëlle M Gerlag1, Paul P Tak.   

Abstract

The analysis of synovial biomarkers is increasingly used in the context of innovative trial design in rheumatoid arthritis (RA). This approach, which is generally well tolerated by patients, has been used to provide insight into the pathogenesis of RA and the mechanism of action of therapy, as well as for screening purposes during early drug development.

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Year:  2008        PMID： 18455687     DOI： 10.1016/j.berh.2008.02.002

Source DB:  PubMed          Journal:  Best Pract Res Clin Rheumatol        ISSN： 1521-6942            Impact factor:   4.098


  17 in total

Review 1.  Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?

Authors:  M D Smith; D Baeten; A-K Ulfgren; I B McInnes; O Fitzgerald; B Bresnihan; P P Tak; D Veale
Journal:  Ann Rheum Dis       Date:  2005-06-23       Impact factor: 19.103

Review 2.  Myeloid Populations in Systemic Autoimmune Diseases.

Authors:  María Morell; Nieves Varela; Concepción Marañón
Journal:  Clin Rev Allergy Immunol       Date:  2017-10       Impact factor: 8.667

Review 3.  Synovial tissue research: a state-of-the-art review.

Authors:  Carl Orr; Elsa Vieira-Sousa; David L Boyle; Maya H Buch; Christopher D Buckley; Juan D Cañete; Anca I Catrina; Ernest H S Choy; Paul Emery; Ursula Fearon; Andrew Filer; Danielle Gerlag; Frances Humby; John D Isaacs; Søren A Just; Bernard R Lauwerys; Benoit Le Goff; Antonio Manzo; Trudy McGarry; Iain B McInnes; Aurélie Najm; Constantino Pitzalis; Arthur Pratt; Malcolm Smith; Paul P Tak; Rogier Thurlings; João E Fonseca; Douglas J Veale; Sander W Tas
Journal:  Nat Rev Rheumatol       Date:  2017-07-13       Impact factor: 20.543

4.  Protective effect of avicularin on rheumatoid arthritis and its associated mechanisms.

Authors:  Wei Wang; Hongxia Zheng; Minwei Zheng; Xiaoxian Liu; Jianning Yu
Journal:  Exp Ther Med       Date:  2018-10-17       Impact factor: 2.447

5.  Rituximab treatment in rheumatoid arthritis: how does it work?

Authors:  Maria Jh Boumans; Paul P Tak
Journal:  Arthritis Res Ther       Date:  2009-11-24       Impact factor: 5.156

Review 6.  The role of biomarkers in the management of patients with rheumatoid arthritis.

Authors:  Jackie Nam; Edith Villeneuve; Paul Emery
Journal:  Curr Rheumatol Rep       Date:  2009-10       Impact factor: 4.592

7.  Loss of phosphoinositide 3-kinase gamma decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritis.

Authors:  Michael Gruen; Christina Rose; Christian König; Mieczyslaw Gajda; Reinhard Wetzker; Rolf Bräuer
Journal:  BMC Musculoskelet Disord       Date:  2010-04-07       Impact factor: 2.362

8.  Soluble biomarkers of cartilage and bone metabolism in early proof of concept trials in psoriatic arthritis: effects of adalimumab versus placebo.

Authors:  Arno W R van Kuijk; Jeroen DeGroot; Rishma C Koeman; Nico Sakkee; Dominique L Baeten; Danielle M Gerlag; Paul P Tak
Journal:  PLoS One       Date:  2010-09-03       Impact factor: 3.240

Review 9.  Synovitis in psoriatic arthritis: immunohistochemistry, comparisons with rheumatoid arthritis, and effects of therapy.

Authors:  Arno W R van Kuijk; Paul P Tak
Journal:  Curr Rheumatol Rep       Date:  2011-08       Impact factor: 4.592

10.  A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue.

Authors:  A W R van Kuijk; D M Gerlag; K Vos; G Wolbink; M de Groot; M A de Rie; A H Zwinderman; B A C Dijkmans; P P Tak
Journal:  Ann Rheum Dis       Date:  2008-07-22       Impact factor: 19.103
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