Literature DB >> 18454273

Acute management of hemodynamically unstable pelvic trauma patients: time for a change? Multicenter review of recent practice.

Diederik O Verbeek, Diederik Verbeek1, Michael Sugrue, Zsolt Balogh, Danny Cass, Ian Civil, Ian Harris, Thomas Kossmann, Steve Leibman, Valerie Malka, Anthony Pohl, Sudhakar Rao, Martin Richardson, Michael Schuetz, Caesar Ursic, Vanessa Wills.   

Abstract

BACKGROUND: Hemorrhage-related mortality (HRM) associated with pelvic fractures continues to challenge trauma care. This study describes the management and outcome of hemodynamically unstable patients with a pelvic fracture, with emphasis on primary intervention for hemorrhage control and HRM.
METHODS: Blunt trauma patients [Injury Severity Score (ISS) >or=16] with a major pelvic fracture (Abbreviated Injury Score, pelvis >or=3) and hemodynamic instability [admission systolic blood pressure (SBP) <or=90 mmHg or receiving >or=6 units of packed red blood cells (PRBCs)/24 hours) were included into a 48-month (ending in December 2003) multicenter retrospective study of 11 major trauma centers. Data are presented as the mean +/- SD.
RESULTS: A total of 217 patients (mean age 41 +/- 19 years, 71% male, ISS 42 +/- 16) were studied. The admission SBP was 96 +/- 37 mmHg and the Glascow Coma Scale (GCS) 11 +/- 5. Patients received 4 +/- 2 liters of fluids including 4 +/- 4 units of PRBCs in the emergency room (ER). In total, 69 (32%) patients died, among whom the HRM was 19%; 29% of the deaths were due to pelvic bleeding. Altogether, 120 of the 217 (55%) patients underwent focused abdominal sonography for trauma (FAST) or diagnostic peritoneal aspiration (DPA) and diagnostic peritoneal lavage (DPL); 60 of the 217 (28%) patients were found to have pelvic binding in the ER. In all, 53 of 109 (49%) patients had no bleeding noted at laparotomy, 26 of 106 (25%) had no abdominal findings, and 15 of 53 (28%) had had no prior abdominal investigation (FAST/DPL/computed tomography). Angiography was positive in 48 of 58 (83%) patients. The HRM was highest in patients with laparotomy as the primary intervention (29%) followed by the angiography group (18%), the combined laparotomy/pelvic fixation group (16%), and the pelvic fixation-only group (10%).
CONCLUSION: HRM associated with major pelvic trauma is unacceptably high especially in the laparotomy group. Hence, nontherapeutic laparotomy must be avoided, concentrating instead on arresting pelvic hemorrhage. Standards of care must be implemented and abided by.

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Year:  2008        PMID: 18454273     DOI: 10.1007/s00268-008-9591-z

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  35 in total

1.  Pelvic fracture pattern does not always predict the need for urgent embolization.

Authors:  Eric L Sarin; John B Moore; Ernest E Moore; Michael R Shannon; Charles E Ray; Steven J Morgan; Wade R Smith
Journal:  J Trauma       Date:  2005-05

2.  Early embolization and vasopressor administration for management of life-threatening hemorrhage from pelvic fracture.

Authors:  Pascal Fangio; Karim Asehnoune; Alain Edouard; Nadia Smail; Dan Benhamou
Journal:  J Trauma       Date:  2005-05

Review 3.  Hypothermia-induced coagulopathies in trauma.

Authors:  A Patt; B L McCroskey; E E Moore
Journal:  Surg Clin North Am       Date:  1988-08       Impact factor: 2.741

4.  Pelvic angiography for recurrent traumatic pelvic arterial hemorrhage.

Authors:  David Gourlay; Eric Hoffer; Milton Routt; Eileen Bulger
Journal:  J Trauma       Date:  2005-11

5.  A prospective study on the safety and efficacy of angiographic embolization for pelvic and visceral injuries.

Authors:  George C Velmahos; Konstantinos G Toutouzas; Pantelis Vassiliu; Grant Sarkisyan; Linda S Chan; Sue H Hanks; Thomas V Berne; Demetrios Demetriades
Journal:  J Trauma       Date:  2002-08

6.  Control of severe hemorrhage using C-clamp and pelvic packing in multiply injured patients with pelvic ring disruption.

Authors:  W Ertel; M Keel; K Eid; A Platz; O Trentz
Journal:  J Orthop Trauma       Date:  2001 Sep-Oct       Impact factor: 2.512

Review 7.  Hemorrhage in pelvic fracture: who needs angiography?

Authors:  Axel Gänsslen; Peter Giannoudis; Hans-Christoph Pape
Journal:  Curr Opin Crit Care       Date:  2003-12       Impact factor: 3.687

8.  The importance of fracture pattern in guiding therapeutic decision-making in patients with hemorrhagic shock and pelvic ring disruptions.

Authors:  Brian J Eastridge; Adam Starr; Joseph P Minei; Grant E O'Keefe; Thomas M Scalea
Journal:  J Trauma       Date:  2002-09

9.  Pelvic fractures: epidemiology and predictors of associated abdominal injuries and outcomes.

Authors:  Demetrios Demetriades; Marios Karaiskakis; Konstantinos Toutouzas; Kathleen Alo; George Velmahos; Linda Chan
Journal:  J Am Coll Surg       Date:  2002-07       Impact factor: 6.113

10.  Pelvic disruption in the polytraumatized patient: a management protocol.

Authors:  R McMurtry; D Walton; D Dickinson; J Kellam; M Tile
Journal:  Clin Orthop Relat Res       Date:  1980-09       Impact factor: 4.176

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  30 in total

1.  Angioembolization and laparotomy for patients with concomitant pelvic arterial hemorrhage and blunt abdominal trauma.

Authors:  Jen-Feng Fang; Lih-Yuann Shih; Yon-Cheong Wong; Being-Chuan Lin; Yu-Pao Hsu
Journal:  Langenbecks Arch Surg       Date:  2010-12-01       Impact factor: 3.445

2.  Predictive parameters for angiography and embolization in the bleeding pelvic fracture.

Authors:  V Anandakumar; Fareed K Hussein; B Varuun; R Zhu
Journal:  J Clin Orthop Trauma       Date:  2013-01-22

Review 3.  Anaesthesia for the management of traumatic pelvic fractures.

Authors:  M A Akuji; E E Chapman; P A D Clements
Journal:  BJA Educ       Date:  2018-05-21

Review 4.  Preperitoneal pelvic packing for exsanguinating pelvic fractures.

Authors:  Clay Cothren Burlew
Journal:  Int Orthop       Date:  2017-04-26       Impact factor: 3.075

Review 5.  Haemorrhage in fragility fractures of the pelvis.

Authors:  S-O Dietz; A Hofmann; P M Rommens
Journal:  Eur J Trauma Emerg Surg       Date:  2014-09-23       Impact factor: 3.693

6.  Preperitoneal pelvic packing reduces mortality in patients with life-threatening hemorrhage due to unstable pelvic fractures.

Authors:  Clay Cothren Burlew; Ernest E Moore; Philip F Stahel; Andrea E Geddes; Amy E Wagenaar; Fredric M Pieracci; Charles J Fox; Eric M Campion; Jeffrey L Johnson; Cyril Mauffrey
Journal:  J Trauma Acute Care Surg       Date:  2017-02       Impact factor: 3.313

7.  The utility of FAST for initial abdominal screening of major pelvic fracture patients.

Authors:  Diederik O F Verbeek; Ijsbrand A J Zijlstra; Christaan van der Leij; Kornelis J Ponsen; Otto M van Delden; J Carel Goslings
Journal:  World J Surg       Date:  2014-07       Impact factor: 3.352

8.  Management of bleeding following major trauma: an updated European guideline.

Authors:  Rolf Rossaint; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Philip F Stahel; Jean-Louis Vincent; Donat R Spahn
Journal:  Crit Care       Date:  2010-04-06       Impact factor: 9.097

9.  [Current treatment of pelvic ring fractures].

Authors:  U Culemann; H J Oestern; T Pohlemann
Journal:  Unfallchirurg       Date:  2014-02       Impact factor: 1.000

Review 10.  Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Authors:  Donat R Spahn; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Jean-Louis Vincent; Rolf Rossaint
Journal:  Crit Care       Date:  2013-04-19       Impact factor: 9.097

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