Literature DB >> 27893645

Preperitoneal pelvic packing reduces mortality in patients with life-threatening hemorrhage due to unstable pelvic fractures.

Clay Cothren Burlew1, Ernest E Moore, Philip F Stahel, Andrea E Geddes, Amy E Wagenaar, Fredric M Pieracci, Charles J Fox, Eric M Campion, Jeffrey L Johnson, Cyril Mauffrey.   

Abstract

BACKGROUND: A 2015 American Association for the Surgery of Trauma trial reported a 32% mortality for pelvic fracture patients in shock. Angioembolization (AE) is the most common intervention; the Maryland group revealed time to AE averaged 5 hours. The goal of this study was to evaluate the time to intervention and outcomes of an alternative approach for pelvic hemorrhage. We hypothesized that preperitoneal pelvic packing (PPP) results in a shorter time to intervention and lower mortality.
METHODS: In 2004, we initiated a PPP protocol for pelvic fracture hemorrhage.
RESULTS: During the 11-year study, 2,293 patients were admitted with pelvic fractures; 128 (6%) patients underwent PPP (mean age, 44 ± 2 years; Injury Severity Score (ISS), 48 ± 1.2). The lowest emergency department systolic blood pressure was 74 mm Hg and highest heart rate was 120. Median time to operation was 44 minutes and 3 additional operations were performed in 109 (85%) patients. Median RBC transfusions before SICU admission compared with the 24 postoperative hours were 8 versus 3 units (p < 0.05). After PPP, 16 (13%) patients underwent AE with a documented arterial blush.Mortality in this high-risk group was 21%. Death was due to brain injury (9), multiple organ failure (4), pulmonary or cardiac failure (6), withdrawal of support (4), adverse physiology (3), and Mucor infection (1). Of those patients with physiologic exhaustion, 2 died in the operating room at 89 and 100 minutes after arrival, whereas 1 died 9 hours after arrival.
CONCLUSIONS: PPP results in a shorter time to intervention and lower mortality compared with modern series using AE. Examining mortality, only 3 (2%) deaths were attributed to the immediate sequelae of bleeding with physiologic failure. With time to death under 100 minutes in 2 patients, AE is unlikely to have been feasible. PPP should be used for pelvic fracture-related bleeding in the patient who remains unstable despite initial transfusion. LEVEL OF EVIDENCE: Therapeutic study, level IV.

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Year:  2017        PMID: 27893645      PMCID: PMC5250563          DOI: 10.1097/TA.0000000000001324

Source DB:  PubMed          Journal:  J Trauma Acute Care Surg        ISSN: 2163-0755            Impact factor:   3.313


  32 in total

1.  Are we delivering two standards of care for pelvic trauma? Availability of angioembolization after hours and on weekends increases time to therapeutic intervention.

Authors:  Diane A Schwartz; Michael Medina; Bryan A Cotton; Elaheh Rahbar; Charles E Wade; Alan M Cohen; Angela M Beeler; Andrew R Burgess; John B Holcomb
Journal:  J Trauma Acute Care Surg       Date:  2014-01       Impact factor: 3.313

Review 2.  External fixation for acute pelvic ring injuries: decision making and technical options.

Authors:  Philip F Stahel; Cyril Mauffrey; Wade R Smith; Jason McKean; Jiandong Hao; Clay Cothren Burlew; Ernest E Moore
Journal:  J Trauma Acute Care Surg       Date:  2013-11       Impact factor: 3.313

3.  Hemodynamically unstable pelvic fractures: recent care and new guidelines.

Authors:  Martin J Heetveld; Ian Harris; Glen Schlaphoff; Zsolt Balogh; Scott K D'Amours; Michael Sugrue
Journal:  World J Surg       Date:  2004-09       Impact factor: 3.352

4.  Retroperitoneal pelvic packing in the management of hemodynamically unstable pelvic fractures: a level I trauma center experience.

Authors:  Dora K C Tai; Wing-Hong Li; Kin-Yan Lee; Mina Cheng; Kin-Bong Lee; Lap-Fai Tang; Albert Kwok-Hung Lai; Hiu-Fai Ho; Moon-Tong Cheung
Journal:  J Trauma       Date:  2011-10

5.  Postmortem angiography and dissection of the hypogastric artery in pelvic fractures.

Authors:  V M Huittinen; P Slätis
Journal:  Surgery       Date:  1973-03       Impact factor: 3.982

Review 6.  Strategies for the management of haemorrhage following pelvic fractures and associated trauma-induced coagulopathy.

Authors:  C Mauffrey; D O Cuellar; F Pieracci; D J Hak; E M Hammerberg; P F Stahel; C C Burlew; E E Moore
Journal:  Bone Joint J       Date:  2014-09       Impact factor: 5.082

7.  The role of associated injuries on outcome of blunt trauma patients sustaining pelvic fractures.

Authors:  J Gustavo Parreira; R Coimbra; S Rasslan; A Oliveira; M Fregoneze; M Mercadante
Journal:  Injury       Date:  2000-11       Impact factor: 2.586

8.  Pelvic fractures: epidemiology and predictors of associated abdominal injuries and outcomes.

Authors:  Demetrios Demetriades; Marios Karaiskakis; Konstantinos Toutouzas; Kathleen Alo; George Velmahos; Linda Chan
Journal:  J Am Coll Surg       Date:  2002-07       Impact factor: 6.113

9.  Efficacy of extra-peritoneal pelvic packing in hemodynamically unstable pelvic fractures, a Propensity Score Analysis.

Authors:  Osvaldo Chiara; Emanuele di Fratta; Anna Mariani; Bertuzzi Michaela; Lucia Prestini; Fabrizio Sammartano; Stefania Cimbanassi
Journal:  World J Emerg Surg       Date:  2016-06-01       Impact factor: 5.469

10.  Preperitoneal pelvic packing in patients with hemodynamic instability due to severe pelvic fracture: early experience in a Korean trauma center.

Authors:  Ji Young Jang; Hongjin Shim; Pil Young Jung; Seongyup Kim; Keum Seok Bae
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2016-01-13       Impact factor: 2.953

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  31 in total

1.  Multicenter retrospective study of noncompressible torso hemorrhage: Anatomic locations of bleeding and comparison of endovascular versus open approach.

Authors:  Ronald Chang; Erin E Fox; Thomas J Greene; Brian J Eastridge; Ramyar Gilani; Kevin K Chung; Stacia M DeSantis; Joseph J DuBose; Jeffrey S Tomasek; Gerald R Fortuna; Valerie G Sams; S Rob Todd; Jeanette M Podbielski; Charles E Wade; John B Holcomb
Journal:  J Trauma Acute Care Surg       Date:  2017-07       Impact factor: 3.313

2.  Occult injuries of the contralateral sacroiliac joint in operatively treated pelvis fractures: incidence, root cause analysis, and proposal of treatment algorithm.

Authors:  Andrew S Maertens; Murphy P Martin; Chase S Dean; David Rojas; Joshua A Parry; Michael Maher; Cyril P Mauffrey
Journal:  Int Orthop       Date:  2018-12-11       Impact factor: 3.075

Review 3.  Preperitoneal pelvic packing for exsanguinating pelvic fractures.

Authors:  Clay Cothren Burlew
Journal:  Int Orthop       Date:  2017-04-26       Impact factor: 3.075

Review 4.  Hemicorporectomy as a life-saving strategy for severe pelvic ring crush injury: a case report.

Authors:  Salin Pereira Warr; Paula M Jaramillo; Sebastian Tobon Franco; Carlos Oliver Valderrama-Molina; Alfredo Constain Franco
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-02-10

5.  Management of pelvi-acetabular injuries: Global scenario and future trends.

Authors:  Vivek Trikha; Paul Tornetta
Journal:  J Clin Orthop Trauma       Date:  2020-10-20

6.  Commentary on "Multidetector CT in Vascular Injuries Resulting from Pelvic Fractures".

Authors:  David Dreizin
Journal:  Radiographics       Date:  2019 Nov-Dec       Impact factor: 5.333

7.  Improvement of outcomes in patients with pelvic fractures and hemodynamic instability after the establishment of a Korean regional trauma center.

Authors:  Ji Young Jang; Hongjin Shim; Hye Youn Kwon; Hoejeong Chung; Pil Young Jung; Seongyup Kim; Hoon Ryu; Keum Seok Bae
Journal:  Eur J Trauma Emerg Surg       Date:  2017-12-27       Impact factor: 3.693

8.  Prospective validation of a new protocol with preperitoneal pelvic packing as the mainstay for the treatment of hemodynamically unstable pelvic trauma: a 5-year experience.

Authors:  Stefano Magnone; Niccolò Allievi; Marco Ceresoli; Federico Coccolini; Michele Pisano; Luca Ansaloni
Journal:  Eur J Trauma Emerg Surg       Date:  2019-04-06       Impact factor: 3.693

Review 9.  Vertical shear pelvic injury: evaluation, management, and fixation strategies.

Authors:  Laura Blum; Mark E Hake; Ryan Charles; Todd Conlan; David Rojas; Murphy Trey Martin; Cyril Mauffrey
Journal:  Int Orthop       Date:  2018-03-26       Impact factor: 3.075

10.  Risk factors for complications and in-hospital mortality: An analysis of 19,834 open pelvic ring fractures.

Authors:  Nicholas Frane; Cesar Iturriaga; Christine Bub; Peter Regala; Gus Katsigiorgis; Michael Linn
Journal:  J Clin Orthop Trauma       Date:  2020-08-25
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