Literature DB >> 18451922

Group refractive index reconstruction with broadband interferometric confocal microscopy.

Daniel L Marks1, Simon C Schlachter, Adam M Zysk, Stephen A Boppart.   

Abstract

We propose a novel method of measuring the group refractive index of biological tissues at the micrometer scale. The technique utilizes a broadband confocal microscope embedded into a Mach-Zehnder interferometer, with which spectral interferograms are measured as the sample is translated through the focus of the beam. The method does not require phase unwrapping and is insensitive to vibrations in the sample and reference arms. High measurement stability is achieved because a single spectral interferogram contains all the information necessary to compute the optical path delay of the beam transmitted through the sample. Included are a physical framework defining the forward problem, linear solutions to the inverse problem, and simulated images of biologically relevant phantoms.

Mesh:

Year:  2008        PMID: 18451922      PMCID: PMC2883334          DOI: 10.1364/josaa.25.001156

Source DB:  PubMed          Journal:  J Opt Soc Am A Opt Image Sci Vis        ISSN: 1084-7529            Impact factor:   2.129


  14 in total

1.  Relation between computed tomography and diffraction tomography.

Authors:  G Gbur; E Wolf
Journal:  J Opt Soc Am A Opt Image Sci Vis       Date:  2001-09       Impact factor: 2.129

2.  Projected index computed tomography.

Authors:  Adam M Zysk; J Josh Reynolds; Daniel L Marks; P Scott Carney; Stephen A Boppart
Journal:  Opt Lett       Date:  2003-05-01       Impact factor: 3.776

3.  Bifocal optical coherenc refractometry of turbid media.

Authors:  Sergey A Alexandrov; Andrei V Zvyagin; K K M B Dilusha Silva; David D Sampson
Journal:  Opt Lett       Date:  2003-01-15       Impact factor: 3.776

4.  Nondestructive measurement of an optical fiber refractive-index profile by a transmitted-light differential interference contact microscope.

Authors:  Zhongyao Liu; Xiaoman Dong; Qianghua Chen; Chunyong Yin; Yuxian Xu; Yingjun Zheng
Journal:  Appl Opt       Date:  2004-03-01       Impact factor: 1.980

5.  Refractive index of carcinogen-induced rat mammary tumours.

Authors:  Adam M Zysk; Eric J Chaney; Stephen A Boppart
Journal:  Phys Med Biol       Date:  2006-04-10       Impact factor: 3.609

6.  Dual-confocal fiber-optic method for absolute measurement of refractive index and thickness of optically transparent media.

Authors:  Ilko K Ilev; Ronald W Waynant; Kimberly R Byrnes; Juanita J Anders
Journal:  Opt Lett       Date:  2002-10-01       Impact factor: 3.776

7.  Tomographic phase microscopy.

Authors:  Wonshik Choi; Christopher Fang-Yen; Kamran Badizadegan; Seungeun Oh; Niyom Lue; Ramachandra R Dasari; Michael S Feld
Journal:  Nat Methods       Date:  2007-08-12       Impact factor: 28.547

8.  Refractive index tomography of turbid media by bifocal optical coherence refractometry.

Authors:  Andrei Zvyagin; K K M B Silva; Sergey Alexandrov; Timothy Hillman; Julian Armstrong; Takuya Tsuzuki; David Sampson
Journal:  Opt Express       Date:  2003-12-15       Impact factor: 3.894

9.  Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm.

Authors:  B Park; Mark C Pierce; Barry Cense; Seok-Hyun Yun; Mircea Mujat; Guillermo Tearney; Brett Bouma; Johannes de Boer
Journal:  Opt Express       Date:  2005-05-30       Impact factor: 3.894

10.  Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography.

Authors:  Jeff Fingler; Dan Schwartz; Changhuei Yang; Scott E Fraser
Journal:  Opt Express       Date:  2007-10-01       Impact factor: 3.894

View more
  1 in total

1.  Plastinated tissue samples as three-dimensional models for optical instrument characterization.

Authors:  Daniel L Marks; Eric J Chaney; Stephen A Boppart
Journal:  Opt Express       Date:  2008-09-29       Impact factor: 3.894

  1 in total

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