Literature DB >> 18450810

quantiNemo: an individual-based program to simulate quantitative traits with explicit genetic architecture in a dynamic metapopulation.

Samuel Neuenschwander1, Frédéric Hospital, Frédéric Guillaume, Jérôme Goudet.   

Abstract

UNLABELLED: quantiNemo is an individual-based, genetically explicit stochastic simulation program. It was developed to investigate the effects of selection, mutation, recombination and drift on quantitative traits with varying architectures in structured populations connected by migration and located in a heterogeneous habitat. quantiNemo is highly flexible at various levels: population, selection, trait(s) architecture, genetic map for QTL and/or markers, environment, demography, mating system, etc. quantiNemo is coded in C++ using an object-oriented approach and runs on any computer platform. AVAILABILITY: Executables for several platforms, user's manual, and source code are freely available under the GNU General Public License at http://www2.unil.ch/popgen/softwares/quantinemo.

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Year:  2008        PMID: 18450810     DOI: 10.1093/bioinformatics/btn219

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  35 in total

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7.  A C++ template library for efficient forward-time population genetic simulation of large populations.

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9.  Influence of mutation rate on estimators of genetic differentiation--lessons from Arabidopsis thaliana.

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