| Literature DB >> 18449504 |
Yuna Kim1, Dokyung Lee, Donghyun Kim, Jooyong Cho, Jaewook Yang, Myungjun Chung, Kyungjae Kim, Namjoo Ha.
Abstract
In this study, we assessed the anticancer activity and bacterial enzyme inhibition of Bifidobacterium adolescentis SPM0212. B. adolescentis SPM0212 inhibited the proliferation of three human colon cancer cell lines: HT-29, SW 480, and Caco-2. SPM0212 also dose-dependently inhibited TNF-á production and changes in cellular morphology. B. adolescentis SPM0212 inhibited harmful fecal enzymes, including â-glucuronidase, â-glucosidase, tryptophanase, and urease. Thus, B. adolescentis SPM0212 exerts an anticancer effect and inhibits harmful fecal enzymes.Entities:
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Year: 2008 PMID： 18449504 DOI： 10.1007/s12272-001-1180-y
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946