| Literature DB >> 18447382 |
Zhen-Ning Sun1, Feng-Qin Liu, Yan Chen, Paul Kwong Hang Tam, Dan Yang.
Abstract
A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H2O2/Cl(-) system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems.Entities:
Mesh:
Substances:
Year: 2008 PMID: 18447382 DOI: 10.1021/ol800507m
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005