Literature DB >> 18444265

Antimycobacterial substances from Phaeosphaeria sp BCC8292.

Pattama Pittayakhajonwut1, Pairoh Sohsomboon, Aibrohim Dramae, Rapheephat Suvannakad, Sanisa Lapanun, Morakot Tantichareon.   

Abstract

Eleven substances including naphthalenones, naphthoquinones, unsymmetrical naphthoquinone dimers and a chlorinated diphenyl ether, three of which are new, have been isolated from the fungus Phaeosphaeria sp. The absolute stereochemistry of naphthalenones has been determined by the Mosher and exciton chirality methods. The biological activity of these compounds against Mycobacterium tuberculosis and cytotoxicity against KB, BCA, NCI-H 187 and Vero cell lines were evaluated.

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Year:  2008        PMID： 18444265     DOI： 10.1055/s-2008-1034300

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  6 in total

1.  Leishmanicidal and antitumoral activities of endophytic fungi associated with the Antarctic angiosperms Deschampsia antarctica Desv. and Colobanthus quitensis (Kunth) Bartl.

Authors:  Iara F Santiago; Tânia M A Alves; Ana Rabello; Policarpo A Sales Junior; Alvaro J Romanha; Carlos L Zani; Carlos A Rosa; Luiz H Rosa
Journal:  Extremophiles       Date:  2011-11-10       Impact factor: 2.395

2.  Neuroprotective Metabolites from Vietnamese Marine Derived Fungi of Aspergillus and Penicillium Genera.

Authors:  Elena V Girich; Anton N Yurchenko; Olga F Smetanina; Phan Thi Hoai Trinh; Ngo Thi Duy Ngoc; Mikhail V Pivkin; Roman S Popov; Evgeny A Pislyagin; Ekaterina S Menchinskaya; Ekaterina A Chingizova; Shamil S Afiyatullov; Ekaterina A Yurchenko
Journal:  Mar Drugs       Date:  2020-11-30       Impact factor: 5.118

3.  Antimicrobial Metabolites against Methicillin-Resistant Staphylococcus aureus from the Endophytic Fungus Neofusicoccum australe.

Authors:  Melissa M Cadelis; Soeren Geese; Benedict B Uy; Daniel R Mulholland; Shara J van de Pas; Alex Grey; Bevan S Weir; Brent R Copp; Siouxsie Wiles
Journal:  Molecules       Date:  2021-02-19       Impact factor: 4.411

Review 4.  Fungal Naphthalenones; Promising Metabolites for Drug Discovery: Structures, Biosynthesis, Sources, and Pharmacological Potential.

Authors:  Sabrin R M Ibrahim; Sana A Fadil; Haifa A Fadil; Bayan A Eshmawi; Shaimaa G A Mohamed; Gamal A Mohamed
Journal:  Toxins (Basel)       Date:  2022-02-19       Impact factor: 4.546

5.  Cytotoxic Naphthoquinone Analogues, Including Heterodimers, and Their Structure Elucidation Using LR-HSQMBC NMR Experiments.

Authors:  Laura Flores-Bocanegra; Huzefa A Raja; Jeffrey W Bacon; Amanda C Maldonado; Joanna E Burdette; Cedric J Pearce; Nicholas H Oberlies
Journal:  J Nat Prod       Date:  2020-10-02       Impact factor: 4.050

Review 6.  Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds.

Authors:  Alfonsus Alvin; Kristin I Miller; Brett A Neilan
Journal:  Microbiol Res       Date:  2014-01-15       Impact factor: 5.415
  6 in total

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