Literature DB >> 18443652

Convenient Synthesis of a Library of Discrete Hydroxamic Acids Using the Hydroxythiophenol (Marshall) Resin.

Jinil Choi1, Jewn Giew Park, Yuan-Ping Pang.   

Abstract

Several resins have reportedly been used to synthesize hydroxamic acids except for the hydroxythiophenol (Marshall) resin. Herein we report the use of the Marshall resin to synthesize hydroxamic acids from carboxylic acids and its application to convert a library of fourteen discrete aliphatic and aromatic carboxylic acids including N-protected amino acids to their corresponding hydroxamic acids in good yields.

Entities:  

Year:  2008        PMID： 18443652      PMCID： PMC2352145          DOI： 10.1016/j.tetlet.2007.12.073

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  24 in total

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